Interactor 1: TPA (P00750)
Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B]
Gene: PLAT

Interactor 2: ST14 (Q9Y5Y6)
Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein)
Gene: ST14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~Trypsin, CUB~Kringle, Kringle~Trypsin, Ldl_recept_a~Trypsin, Trypsin~Trypsin
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0006508 - proteolysis
Homologous interactions 15

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024