Interactor 1: CO3 (P01026)
Complement C3 [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc) (Neutrophil chemotactic factor-2) (ENCF-2); Complement C3 alpha chain; C3a anaphylatoxin (Neutrophil chemotactic factor-1) (ENCF-1); Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]
Gene: C3
Interactor 2: Q6MG73 (Q6MG73)
Complement C2 (EC 3.4.21.43) (C3/C5 convertase)
Gene: C2
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9688553 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | A2M~Sushi, A2M_BRD~Sushi, A2M_recep~Trypsin, MG1~Sushi, MG1~Trypsin, MG2~Sushi, MG2~Trypsin, MG4~Sushi, NTR~Sushi, NTR~VWA, Sushi~TED_complement, TED_complement~VWA |
| Common GO terms | GO:0006956 - complement activation GO:0006958 - complement activation, classical pathway GO:0009617 - response to bacterium GO:2000427 - positive regulation of apoptotic cell clearance |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
