HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	10777532, 20195357
Identification Methods	two hybrid, pull down, display technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 2514
+	Hs
		1317574 BACH2_HUMAN (14-307): 4.1e-34: 136: 13.65		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		402682 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261583 BACH2_HUMAN (14-307): 4.1e-34: 136: 13.65		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		157162 BACH1_HUMAN (4-295): 1.68e-30: 125: 12.99		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Mm
		956178 BACH1_MOUSE (4-304): 5.82e-27: 114: 14.16		NCOR1_MOUSE (1-2514): 8.41e-128: 453: 34.08
+	Hs
		345526 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		345491 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		402605 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		568277 ATF7_HUMAN (82-289): 7.9e-31: 124: 16.59		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		973616 CREB5_HUMAN (92-233): 1.13e-24: 107: 19.01		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		402371 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		402260 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93
+	Hs
		401830 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		MAP1A_HUMAN (477-2485): 7.65e-16: 87.1: 9.73