HitPredict

Interactor 1: FOS (P01101)
Protein c-Fos (Cellular oncogene fos) (FBJ osteosarcoma oncogene) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: JUN (P05627)
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)
Gene: JUN

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 1631061, 21478324, 15867431, 36629882, 12145309, 19251936, 19592489
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_1
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
and 17 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 380
Mm

1 334
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024