HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	29467282, 36424410, 17314511, 21988832
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 439
+	Hs
		346411 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60
+	Hs
		346412 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39
+	Hs
		346168 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59
+	Hs
		346331 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TERA_HUMAN (162-434): 9.21e-77: 256: 35.17
+	Hs
		347346 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		AFG2A_HUMAN (182-435): 3.65e-68: 234: 35.32
+	Hs
		379205 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60
+	Hs
		379206 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39
+	Hs
		573015 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		PRS6A_HUMAN (1-439): 1.23e-136: 401: 100.00