HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CASPE (P31944)
Caspase-14 (CASP-14) (EC 3.4.22.-) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]
Gene: CASP14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 242
+	Hs
		346803 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CASP8_HUMAN (12-241): 7.41e-80: 249: 29.58
+	Hs
		346337 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CASP6_HUMAN (8-241): 7.15e-80: 243: 28.46
+	Hs
		347111 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CASPC_HUMAN (20-241): 7.64e-75: 232: 22.22
+	Hs
		379059 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CASPE_HUMAN (1-242): 8.94e-98: 286: 100.00
+	Hs
		379526 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CASPC_HUMAN (20-241): 7.64e-75: 232: 22.22
+	Hs
		788187 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		CASP3_HUMAN (11-241): 2.94e-87: 261: 29.80