HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	29467282, 30415952, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 863
+	Hs
		346235 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM2_HUMAN (2-839): 0: 762: 27.95
+	Hs
		346066 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM5_HUMAN (133-846): 0: 698: 30.23
+	Hs
		346783 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM6_HUMAN (138-842): 0: 675: 26.97
+	Hs
		346067 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM7_HUMAN (158-841): 0: 660: 29.88
+	Hs
		379063 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MCM7_HUMAN (158-841): 0: 660: 29.88