HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MSH6 (P52701)
DNA mismatch repair protein Msh6 (hMSH6) (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)
Gene: MSH6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	17353931, 29467282, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1360
+	Hs
		345909 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MSH3_HUMAN (173-1357): 0: 835: 22.16
+	Hs
		346161 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Hs
		794224 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		MSH2_HUMAN (393-1360): 0: 824: 21.88
+	Hs
		347824 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NSD3_HUMAN (4-390): 2.84e-86: 311: 19.51