Protein: PLK2
Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (hPlk2) (Serine/threonine-protein kinase SNK) (hSNK) (Serum-inducible kinase)

Gene: PLK2
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q9NYY3

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000922 - spindle pole
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

167024

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

3

6

High-throughput

0.861

High

1026952

PAK2
Serine/threonine-protein kinase PAK 2

3

17

High-throughput

0.861

High

1237557

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

3

6

High-throughput

0.770

High

159278

CSKP
Peripheral plasma membrane protein CASK

1

20

High-throughput

0.698

High

861949

PLK1
Serine/threonine-protein kinase PLK1

1

17

Small-scale

0.692

High

498363

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

6

High-throughput

0.691

High

1172943

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

1

12

High-throughput

0.691

High

271897

SPB7
Serpin B7

3

3

High-throughput

0.667

High

1243659

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

3

1

High-throughput

0.667

High

742568

SYUA
Alpha-synuclein

3

5

Small-scale

0.651

High

1328674

RNAS7
Ribonuclease 7

3

0

High-throughput

0.638

High

1306633

CIB1
Calcium and integrin-binding protein 1

1

20

Small-scale

0.618

High

984455

EF1A2
Elongation factor 1-alpha 2

2

1

High-throughput

0.611

High

1192643

TAF8
Transcription initiation factor TFIID subunit 8

2

1

High-throughput

0.611

High

245850

CATL2
Cathepsin L2

3

1

High-throughput

0.609

High

1218306

SPA12
Serpin A12

3

3

High-throughput

0.609

High

1220004

SUGP1
SURP and G-patch domain-containing protein 1

3

2

High-throughput

0.609

High

1348717

CBPA4
Carboxypeptidase A4

3

2

High-throughput

0.609

High

1113976

RABL6
Rab-like protein 6

2

0

High-throughput

0.585

High

1205210

CD20B
Cell division cycle protein 20 homolog B

1

10

High-throughput

0.573

High

1267564

TSC1
Hamartin

1

10

Small-scale

0.561

High

344246

A1AT
Alpha-1-antitrypsin

2

3

High-throughput

0.558

High

470182

H2AZ
Histone H2A.Z

1

10

High-throughput

0.536

High

1087119

H2A2C
Histone H2A type 2-C

1

6

High-throughput

0.536

High

1197595

PCGF5
Polycomb group RING finger protein 5

1

7

High-throughput

0.536

High

1268102

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.536

High

1316993

LOXE3
Hydroperoxide isomerase ALOXE3

1

3

High-throughput

0.536

High

1348719

TR150
Thyroid hormone receptor-associated protein 3

1

6

High-throughput

0.536

High

819677

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.518

High

532850

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.513

High

1328448

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.513

High

395925

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

808297

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

5

High-throughput

0.501

High

835119

TSC2
Tuberin

1

4

Small-scale

0.501

High

1335844

CENPJ
Centromere protein J

1

6

Small-scale

0.501

High

1032765

MPP3
MAGUK p55 subfamily member 3

1

11

High-throughput

0.494

High

50364

CA226
Uncharacterized protein C1orf226

1

1

High-throughput

0.489

High

1056331

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

5

High-throughput

0.489

High

1218408

MFN1
Mitofusin-1

1

1

High-throughput

0.489

High

1262916

RT4I1
Reticulon-4-interacting protein 1, mitochondrial

1

1

High-throughput

0.489

High

1264980

IRGQ
Immunity-related GTPase family Q protein

1

3

High-throughput

0.489

High

1348716

CATZ
Cathepsin Z

1

4

High-throughput

0.489

High

163384

XPO1
Exportin-1

1

6

High-throughput

0.479

High

684360

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

843935

FXR1
RNA-binding protein FXR1

1

12

High-throughput

0.479

High

910097

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.479

High

929085

SKP1
S-phase kinase-associated protein 1

1

4

Small-scale

0.479

High

941515

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

1281434

FBXW7
F-box/WD repeat-containing protein 7

1

8

Small-scale

0.479

High

1348720

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.479

High

242771

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

110866

H7C4S4
FMR1 autosomal homolog 1

1

6

High-throughput

0.445

High

305826

ELP1
Elongator complex protein 1

1

0

High-throughput

0.438

High

836339

KLK7
Kallikrein-7

1

1

High-throughput

0.437

High

983017

CSTF1
Cleavage stimulation factor subunit 1

1

4

High-throughput

0.437

High

1348718

DLGP4
Disks large-associated protein 4

1

3

High-throughput

0.417

High

1174743

CENPU
Centromere protein U

1

2

Small-scale

0.408

High

353566

IGKC
Immunoglobulin kappa constant

1

1

High-throughput

0.407

High

1261828

POF1B
Protein POF1B

3

0

High-throughput

0.347

High

1286117

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.279

Low

1198327

RN180
E3 ubiquitin-protein ligase RNF180

1

0

Small-scale

0.249

Low

1260028

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024