Protein: API5
Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)

Gene: API5
Organism: Homo sapiens
Interactions: 156
UniProt ID: Q9BZZ5

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005737 - cytoplasm
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1118156

DX39B
Spliceosome RNA helicase DDX39B

3

4

High-throughput

0.662

High

1420407

ACINU
Apoptotic chromatin condensation inducer in the nucleus

3

3

Small-scale

0.650

High

530343

TAU
Microtubule-associated protein tau

3

0

High-throughput

0.597

High

1111251

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.585

High

242844

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

50139

BICL2
BICD family-like cargo adapter 2

2

0

High-throughput

0.580

High

156077

SOCS6
Suppressor of cytokine signaling 6

2

0

High-throughput

0.576

High

1404371

CDC5L
Cell division cycle 5-like protein

2

0

High-throughput

0.559

High

1420397

API5
Apoptosis inhibitor 5

2

0

Small-scale

0.559

High

1420402

MCM9
DNA helicase MCM9

2

0

Small-scale

0.559

High

396889

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

1198658

NCBP3
Nuclear cap-binding protein subunit 3

2

0

High-throughput

0.547

High

478200

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

1160284

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

High-throughput

0.536

High

361353

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

484638

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

540083

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.513

High

574463

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

1155735

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.513

High

1389763

RBM33
RNA-binding protein 33

1

0

High-throughput

0.513

High

1391954

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

1420411

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.513

High

185997

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

1225851

FRG2
Protein FRG2

1

0

High-throughput

0.493

High

1331151

CE112
Centrosomal protein of 112 kDa

1

0

High-throughput

0.493

High

1391559

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.493

High

1420404

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

123178

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.479

High

207644

DHX15
ATP-dependent RNA helicase DHX15

1

1

High-throughput

0.479

High

285461

EED
Polycomb protein EED

1

2

High-throughput

0.479

High

315989

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

346294

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

550456

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.479

High

576535

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

1

High-throughput

0.479

High

620573

NUCL
Nucleolin

1

1

High-throughput

0.479

High

650946

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.479

High

691403

1433T
14-3-3 protein theta

1

2

High-throughput

0.479

High

731593

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

807572

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.479

High

854928

RECQ1
ATP-dependent DNA helicase Q1

1

2

High-throughput

0.479

High

910676

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.479

High

930046

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

965870

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

High-throughput

0.479

High

966846

1433G
14-3-3 protein gamma

1

2

High-throughput

0.479

High

1062636

DHX9
ATP-dependent RNA helicase A

1

1

High-throughput

0.479

High

1088548

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

1089853

ILF3
Interleukin enhancer-binding factor 3

1

2

High-throughput

0.479

High

1132955

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

1145355

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.479

High

1146808

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.479

High

1148558

SF3B4
Splicing factor 3B subunit 4

1

1

High-throughput

0.479

High

1276753

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1292510

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

3

Small-scale

0.479

High

1392232

DDX27
Probable ATP-dependent RNA helicase DDX27

1

2

High-throughput

0.479

High

1394578

THOC3
THO complex subunit 3

1

1

High-throughput

0.479

High

1420398

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

1

High-throughput

0.479

High

1420403

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1420410

TR150
Thyroid hormone receptor-associated protein 3

1

1

High-throughput

0.479

High

134859

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

141652

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.458

High

143694

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

High-throughput

0.458

High

174397

ZN609
Zinc finger protein 609

1

0

High-throughput

0.458

High

238607

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

248079

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

256552

PRAM2
PRAME family member 2

1

0

Small-scale

0.458

High

260418

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

347916

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

363827

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

412573

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

428962

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

447409

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

474264

NFIC
Nuclear factor 1 C-type

1

0

High-throughput

0.458

High

476026

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

0

High-throughput

0.458

High

567478

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

573237

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

586876

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

589620

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

611973

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

612773

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

696435

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

716965

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.458

High

718843

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

765016

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

774606

BASI
Basigin

1

0

High-throughput

0.458

High

785425

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

810352

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

824345

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.458

High

842526

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

859689

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.458

High

859985

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.458

High

900145

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.458

High

948619

HILS1
Putative histone H1.9

1

0

High-throughput

0.458

High

959951

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

960875

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.458

High

961395

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.458

High

965217

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

969424

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.458

High

969685

RS15A
Small ribosomal subunit protein uS8

1

0

High-throughput

0.458

High

970091

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

971968

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

977360

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

981956

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

985868

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

986190

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.458

High

994781

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

998777

H31
Histone H3.1

1

0

High-throughput

0.458

High

1013860

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

1027734

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.458

High

1033207

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1033773

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1039385

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1051310

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.458

High

1057894

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

1067691

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1089007

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1107183

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1133168

LASP1
LIM and SH3 domain protein 1

1

0

Small-scale

0.458

High

1148651

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

1187074

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

1255427

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1272117

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.458

High

1274048

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.458

High

1313410

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1314049

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

1332712

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.458

High

1364579

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1402564

SRPK1
SRSF protein kinase 1

1

0

High-throughput

0.458

High

1407697

EBP2
Probable rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

1407860

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1416247

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.458

High

1417463

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1420399

REN3A
Regulator of nonsense transcripts 3A

1

0

High-throughput

0.458

High

1420400

PININ
Pinin

1

0

High-throughput

0.458

High

1420405

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1420406

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.458

High

1420408

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

1420409

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

1420412

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.458

High

1420413

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

843956

HD
Huntingtin

1

0

High-throughput

0.438

High

397980

ANGI
Angiogenin

1

0

High-throughput

0.426

High

1034524

TAGL
Transgelin

1

0

High-throughput

0.426

High

1209627

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1292289

S2611
Sodium-independent sulfate anion transporter

1

0

High-throughput

0.426

High

1253739

RHG36
Rho GTPase-activating protein 36

2

0

High-throughput

0.298

High

1398834

DOCK7
Dedicator of cytokinesis protein 7

2

0

High-throughput

0.298

High

1013335

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1420401

OSGL1
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

1

0

High-throughput

0.269

Low

622266

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

769106

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1063601

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.249

Low

1336246

LIPB2
Liprin-beta-2

1

0

High-throughput

0.249

Low

1350829

DYH3
Dynein axonemal heavy chain 3

1

0

High-throughput

0.249

Low

1407340

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.249

Low

1391034

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025