HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CRIP2 (P52943)
Cysteine-rich protein 2 (CRP-2) (Protein ESP1)
Gene: CRIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 208
+	Hs
		347985 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PDLI7_HUMAN (2-124): 1.4e-22: 96.3: 17.89
+	Hs
		348158 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIMA1_HUMAN (3-107): 2.1e-19: 87.6: 29.52
+	Hs
		150500 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ABLM1_HUMAN (56-194): 8.84e-15: 73.9: 15.44
+	Hs
		346895 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CSRP2_HUMAN (121-208): 1.65e-14: 70.5: 39.33
+	Hs
		345915 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CSRP1_HUMAN (2-80): 3.51e-11: 61.6: 41.77
+	Hs
		379158 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CRIP2_HUMAN (1-208): 2.3e-53: 171: 100.00
+	Hs
		379134 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CRIP1_HUMAN (3-78): 1.67e-24: 93.4: 68.42
+	Hs
		379989 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		LIMA1_HUMAN (3-107): 2.1e-19: 87.6: 29.52
+	Hs
		379451 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CSRP2_HUMAN (121-208): 1.65e-14: 70.5: 39.33
+	Hs
		1016076 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		ABLM2_HUMAN (5-115): 1.17e-19: 88.2: 24.32
+	Hs
		150561 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		ABLM1_HUMAN (56-194): 8.84e-15: 73.9: 15.44