Protein: TRBP2
RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)

Gene: TRBP2, TARBP2
Organism: Homo sapiens
Interactions: 149
UniProt ID: Q15633

Gene Ontology (top 5):
GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1150713

DICER
Endoribonuclease Dicer

13

20

Small-scale

0.981

High

286997

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

9

19

Small-scale

0.977

High

1150708

AGO2
Protein argonaute-2

9

15

Small-scale

0.970

High

1150646

TRBP2
RISC-loading complex subunit TARBP2

7

18

Small-scale

0.958

High

624071

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

4

13

Small-scale

0.915

High

1150686

STRBP
Spermatid perinuclear RNA-binding protein

4

18

High-throughput

0.909

High

1150709

AGO1
Protein argonaute-1

4

15

Small-scale

0.900

High

345872

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

18

High-throughput

0.789

High

1008743

RED1
Double-stranded RNA-specific editase 1

2

19

High-throughput

0.783

High

1150699

ZMAT3
Zinc finger matrin-type protein 3

5

15

High-throughput

0.714

High

170156

AURKA
Aurora kinase A

4

3

High-throughput

0.694

High

824166

RL13A
Large ribosomal subunit protein uL13

1

6

High-throughput

0.691

High

937260

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

20

Small-scale

0.691

High

1062476

DHX9
ATP-dependent RNA helicase A

1

20

High-throughput

0.691

High

1089678

ILF3
Interleukin enhancer-binding factor 3

1

19

High-throughput

0.691

High

1150700

AGO4
Protein argonaute-4

1

15

High-throughput

0.691

High

1150669

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

3

5

High-throughput

0.675

High

1150710

ZN346
Zinc finger protein 346

3

20

High-throughput

0.675

High

1089415

ILF2
Interleukin enhancer-binding factor 2

3

20

High-throughput

0.667

High

1150649

FX4L6
Forkhead box protein D4-like 6

3

13

High-throughput

0.667

High

1150680

ZN669
Zinc finger protein 669

2

13

High-throughput

0.628

High

315625

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.618

High

1150691

DDX50
ATP-dependent RNA helicase DDX50

1

20

High-throughput

0.618

High

1150698

AGO3
Protein argonaute-3

1

15

High-throughput

0.618

High

1113187

CUL3
Cullin-3

2

14

High-throughput

0.611

High

1150098

TCEA2
Transcription elongation factor A protein 2

2

5

High-throughput

0.606

High

1150697

ZMAT4
Zinc finger matrin-type protein 4

2

20

High-throughput

0.606

High

1150663

TRM2A
tRNA

2

0

High-throughput

0.602

High

686181

RL13
Large ribosomal subunit protein eL13

2

6

High-throughput

0.601

High

1150665

PNKD
Probable thioesterase PNKD

2

0

High-throughput

0.585

High

1150715

MEMO1
Protein MEMO1

2

0

High-throughput

0.585

High

1150687

PNKP
Bifunctional polynucleotide phosphatase/kinase

2

0

High-throughput

0.580

High

1103693

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

3

High-throughput

0.576

High

1150667

RP25L
Ribonuclease P protein subunit p25-like protein

2

0

High-throughput

0.576

High

1150666

CBPA6
Carboxypeptidase A6

2

1

High-throughput

0.574

High

396183

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1150694

SFXN3
Sideroflexin-3

2

2

High-throughput

0.558

High

1150683

DDX27
Probable ATP-dependent RNA helicase DDX27

1

20

High-throughput

0.553

High

1150719

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.541

High

1150657

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.536

High

191655

MAGB2
Melanoma-associated antigen B2

1

14

High-throughput

0.536

High

755931

MCM5
DNA replication licensing factor MCM5

1

11

High-throughput

0.536

High

785191

RL4
Large ribosomal subunit protein uL4

1

5

High-throughput

0.536

High

842385

RL35
Large ribosomal subunit protein uL29

1

4

High-throughput

0.536

High

884098

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.536

High

960744

RL15
Large ribosomal subunit protein eL15

1

4

High-throughput

0.536

High

969879

RS16
Small ribosomal subunit protein uS9

1

9

High-throughput

0.536

High

1099365

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1106195

MYO9B
Unconventional myosin-IXb

1

3

High-throughput

0.536

High

1126412

CAPR1
Caprin-1

1

5

High-throughput

0.536

High

1150671

TRI41
E3 ubiquitin-protein ligase TRIM41

1

3

High-throughput

0.536

High

1150673

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1150682

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.536

High

1150701

SSF1
Suppressor of SWI4 1 homolog

1

6

High-throughput

0.536

High

1150702

EMIL3
EMILIN-3

1

4

High-throughput

0.536

High

1150712

ABT1
Activator of basal transcription 1

1

7

High-throughput

0.536

High

415591

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

1108346

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.518

High

1150676

NGN1
Neurogenin-1

1

0

High-throughput

0.518

High

1150695

TGIF2
Homeobox protein TGIF2

1

0

High-throughput

0.518

High

1150714

CSEN
Calsenilin

1

0

High-throughput

0.518

High

66790

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.513

High

210282

PHF1
PHD finger protein 1

1

0

High-throughput

0.513

High

567404

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.513

High

1150661

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1150718

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.513

High

913653

VAV2
Guanine nucleotide exchange factor VAV2

1

3

High-throughput

0.508

High

185725

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

10

High-throughput

0.501

High

422152

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

1150685

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

9

High-throughput

0.501

High

273765

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

1

High-throughput

0.489

High

1150656

RHG36
Rho GTPase-activating protein 36

1

9

High-throughput

0.489

High

1150658

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

1

High-throughput

0.489

High

1150706

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.489

High

183003

NKRF
NF-kappa-B-repressing factor

1

7

High-throughput

0.481

High

897834

CDK9
Cyclin-dependent kinase 9

1

12

Small-scale

0.481

High

96688

E9PAV9
G patch domain-containing protein 4

1

8

High-throughput

0.479

High

182303

WDR46
WD repeat-containing protein 46

1

19

High-throughput

0.479

High

194209

R113A
E3 ubiquitin-protein ligase RNF113A

1

4

High-throughput

0.479

High

228719

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

16

High-throughput

0.479

High

303564

SRP72
Signal recognition particle subunit SRP72

1

4

High-throughput

0.479

High

342195

BRD1
Bromodomain-containing protein 1

1

7

High-throughput

0.479

High

372115

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.479

High

400882

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

406218

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.479

High

582809

EZRI
Ezrin

1

12

High-throughput

0.479

High

810122

RL3
Large ribosomal subunit protein uL3

1

7

High-throughput

0.479

High

857462

NOTC1
Neurogenic locus notch homolog protein 1

1

6

Small-scale

0.479

High

872360

SOX2
Transcription factor SOX-2

1

14

High-throughput

0.479

High

919986

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

956155

SRP54
Signal recognition particle subunit SRP54

1

3

High-throughput

0.479

High

1024594

VIGLN
Vigilin

1

20

High-throughput

0.479

High

1034576

AK17A
A-kinase anchor protein 17A

1

7

High-throughput

0.479

High

1043682

CEBPZ
CCAAT/enhancer-binding protein zeta

1

4

High-throughput

0.479

High

1054715

SUH
Recombining binding protein suppressor of hairless

1

5

Small-scale

0.479

High

1091810

TP4A2
Protein tyrosine phosphatase type IVA 2

1

4

High-throughput

0.479

High

1105022

TCOF
Treacle protein

1

17

High-throughput

0.479

High

1107657

MTM1
Myotubularin

1

1

High-throughput

0.479

High

1130269

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

14

High-throughput

0.479

High

1150648

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

8

High-throughput

0.479

High

1150650

RRP12
RRP12-like protein

1

2

High-throughput

0.479

High

1150651

HP1B3
Heterochromatin protein 1-binding protein 3

1

4

High-throughput

0.479

High

1150670

NOC3L
Nucleolar complex protein 3 homolog

1

13

High-throughput

0.479

High

1150674

MAML1
Mastermind-like protein 1

1

9

Small-scale

0.479

High

1150675

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1150677

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

5

High-throughput

0.479

High

1150678

FUBP2
Far upstream element-binding protein 2

1

20

Small-scale

0.479

High

1150688

DNJC2
DnaJ homolog subfamily C member 2

1

8

High-throughput

0.479

High

1150689

POP1
Ribonucleases P/MRP protein subunit POP1

1

4

High-throughput

0.479

High

1150690

RBM4B
RNA-binding protein 4B

1

20

High-throughput

0.479

High

1150696

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1150703

SDA1
Protein SDA1 homolog

1

3

High-throughput

0.479

High

1150705

TRM1
tRNA

1

3

High-throughput

0.479

High

1150717

TRAF6
TNF receptor-associated factor 6

1

19

Small-scale

0.479

High

946113

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.458

High

1150679

IRF7
Interferon regulatory factor 7

1

0

Small-scale

0.458

High

208266

RRP8
Ribosomal RNA-processing protein 8

1

5

High-throughput

0.445

High

254147

CTND1
Catenin delta-1

1

6

High-throughput

0.445

High

288657

NPM3
Nucleoplasmin-3

1

10

High-throughput

0.445

High

601692

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

985680

RL11
Large ribosomal subunit protein uL5

1

5

High-throughput

0.445

High

1037164

H11
Histone H1.1

1

15

High-throughput

0.445

High

1037509

RL18A
Large ribosomal subunit protein eL20

1

5

High-throughput

0.445

High

1136774

MO4L2
Mortality factor 4-like protein 2

1

1

High-throughput

0.445

High

1150647

CIP4
Cdc42-interacting protein 4

1

5

High-throughput

0.445

High

1150653

PKHA7
Pleckstrin homology domain-containing family A member 7

1

17

High-throughput

0.445

High

1150654

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1150655

LN28B
Protein lin-28 homolog B

1

20

High-throughput

0.445

High

1150659

ZN467
Zinc finger protein 467

1

20

High-throughput

0.445

High

1150660

ATCAY
Caytaxin

1

1

High-throughput

0.445

High

1150662

YAF2
YY1-associated factor 2

1

2

High-throughput

0.445

High

1150664

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1150668

RNF10
E3 ubiquitin-protein ligase RNF10

1

4

High-throughput

0.445

High

1150681

HDA11
Histone deacetylase 11

1

9

High-throughput

0.445

High

1150693

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

14

High-throughput

0.445

High

1150707

NXF1
Nuclear RNA export factor 1

1

4

High-throughput

0.445

High

1150716

RBMX2
RNA-binding motif protein, X-linked 2

1

20

High-throughput

0.445

High

105989

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

469086

SRPRA
Signal recognition particle receptor subunit alpha

1

3

High-throughput

0.437

High

1150692

MMTA2
Multiple myeloma tumor-associated protein 2

1

3

High-throughput

0.437

High

1150704

RBM28
RNA-binding protein 28

1

20

High-throughput

0.437

High

1150711

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.437

High

542043

TOP1
DNA topoisomerase 1

1

6

Small-scale

0.408

High

72777

B0UZZ8
WD repeat-containing protein 46

1

19

High-throughput

0.407

High

1150684

MF14A
Hippocampus abundant transcript 1 protein

1

1

High-throughput

0.407

High

1150672

HPSE2
Inactive heparanase-2

1

0

High-throughput

0.279

Low

1150652

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

167449

WNT9A
Protein Wnt-9a

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025