HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CSTF1 (Q05048)
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)
Gene: CSTF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 431
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (136-429): 9.55e-76: 243: 19.81
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (247-429): 1.25e-46: 169: 18.48
+	Hs
		346933 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMU1_HUMAN (253-429): 5.21e-28: 117: 19.02
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (2-196): 1.37e-19: 93.3: 12.75
+	Hs
		196936 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP4_HUMAN (305-429): 8.1e-15: 78.2: 20.47
+	Hs
		348226 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP19_HUMAN (136-335): 3.89e-14: 76.3: 24.50
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		379460 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMU1_HUMAN (253-429): 5.21e-28: 117: 19.02
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75
+	Hs
		380015 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRP19_HUMAN (136-335): 3.89e-14: 76.3: 24.50
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (2-196): 1.37e-19: 93.3: 12.75
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (2-196): 1.37e-19: 93.3: 12.75
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75