HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29467282, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 876
+	Hs
		1016065 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		IMB1_HUMAN (1-876): 0: 635: 100.00
+	Dm
		185888 Q8SY46_DROME (358-449): 1.61e-21: 99.4: 29.03		IMB_DROME (1-875): 0: 590: 61.42
+	Hs
		312153 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IPO7_HUMAN (3-848): 8.3e-82: 286: 12.03
+	Hs
		268567 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SF3B1_HUMAN (146-866): 1.96e-78: 279: 12.23
+	Hs
		347506 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21
+	Hs
		268572 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SF3B1_HUMAN (146-866): 1.96e-78: 279: 12.23
+	Hs
		127155 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IPO5_HUMAN (89-863): 6.82e-13: 75: 10.97