HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: UBP45 (Q70EL2)
Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45)
Gene: USP45

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	36765885
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 814
+	Hs
		348369 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97
+	Hs
		347416 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP33_HUMAN (8-812): 9.02e-121: 388: 18.62
+	Hs
		346277 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP11_HUMAN (172-812): 6.85e-118: 381: 16.74
+	Hs
		347373 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP32_HUMAN (78-729): 2.39e-94: 325: 15.10
+	Hs
		347510 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP13_HUMAN (28-813): 6.12e-75: 263: 12.58
+	Hs
		296257 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP1_HUMAN (134-793): 8.29e-72: 253: 18.04
+	Hs
		346171 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP5_HUMAN (14-552): 2.13e-71: 253: 12.65
+	Hs
		379146 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP11_HUMAN (172-812): 6.85e-118: 381: 16.74
+	Hs
		348252 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP22_HUMAN (444-814): 1.04e-49: 185: 16.01
+	Hs
		271012 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP2_HUMAN (588-811): 1.06e-45: 175: 25.22
+	Hs
		348388 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP3_HUMAN (469-810): 8.99e-42: 162: 18.61
+	Hs
		379106 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP5_HUMAN (14-552): 2.13e-71: 253: 12.65
+	Hs
		64198 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP27_HUMAN (619-812): 3.24e-14: 77.8: 25.49
+	Hs
		607792 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		UBP5_HUMAN (14-552): 2.13e-71: 253: 12.65
+	Hs
		252929 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		UBP13_HUMAN (28-813): 6.12e-75: 263: 12.58
+	Hs
		296287 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		UBP1_HUMAN (134-793): 8.29e-72: 253: 18.04