HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: IQGA3 (Q86VI3)
Ras GTPase-activating-like protein IQGAP3
Gene: IQGAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17314511
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0010628 - positive regulation of gene expression GO:0070371 - ERK1 and ERK2 cascade
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1631
+	Hs
		346191 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Hs
		346724 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IQGA2_HUMAN (86-1631): 0: 1356: 42.50
+	Hs
		346786 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RASA3_HUMAN (841-1504): 2.12e-105: 359: 13.68
+	Hs
		347982 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5C_HUMAN (699-1500): 3.33e-96: 346: 12.52
+	Hs
		346839 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RASA2_HUMAN (847-1499): 5.65e-95: 329: 14.27
+	Hs
		348342 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5A_HUMAN (685-1556): 7.11e-89: 323: 14.90
+	Hs
		348182 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Hs
		346855 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CNN3_HUMAN (1-310): 1.99e-75: 256: 16.98
+	Hs
		345917 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57