Protein: STXB2
Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B)

Gene: STXB2, STXBP2
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q15833

Gene Ontology (top 5):
GO:0001909 - leukocyte mediated cytotoxicity
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1100666

STX3
Syntaxin-3

7

20

Small-scale

0.962

High

286656

STX11
Syntaxin-11

5

20

Small-scale

0.919

High

1154495

STX19
Syntaxin-19

3

20

High-throughput

0.861

High

746199

STX2
Syntaxin-2

1

20

High-throughput

0.691

High

603997

CXA1
Gap junction alpha-1 protein

3

9

High-throughput

0.667

High

347051

BAG2
BAG family molecular chaperone regulator 2

3

1

High-throughput

0.662

High

361260

SODC
Superoxide dismutase [Cu-Zn]

2

1

High-throughput

0.628

High

1106159

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

2

1

High-throughput

0.628

High

963423

STXB1
Syntaxin-binding protein 1

1

3

High-throughput

0.618

High

733358

CCR1
C-C chemokine receptor type 1

2

0

High-throughput

0.602

High

1154493

SPA24
Spermatogenesis-associated protein 24

2

0

High-throughput

0.602

High

1154490

CERS6
Ceramide synthase 6

2

2

High-throughput

0.549

High

445182

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

686818

S10A4
Protein S100-A4

1

1

High-throughput

0.536

High

1154488

SYT6
Synaptotagmin-6

1

1

High-throughput

0.536

High

1154489

PLPP4
Phospholipid phosphatase 4

1

3

High-throughput

0.536

High

1154502

HVCN1
Voltage-gated hydrogen channel 1

1

2

High-throughput

0.536

High

1154506

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.536

High

573490

ENPL
Endoplasmin

1

6

High-throughput

0.515

High

914050

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

1154501

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1154511

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1154512

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

1154494

PHTF2
Protein PHTF2

1

1

High-throughput

0.489

High

1154499

S39A7
Zinc transporter SLC39A7

1

6

High-throughput

0.489

High

1154504

CERS2
Ceramide synthase 2

1

2

High-throughput

0.489

High

1154505

CXD4
Gap junction delta-4 protein

1

9

High-throughput

0.489

High

1154510

GSX1
GS homeobox 1

1

1

High-throughput

0.489

High

378568

IL1B
Interleukin-1 beta

1

1

Small-scale

0.479

High

942635

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

1067378

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1104194

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1140329

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1154498

NUDC2
NudC domain-containing protein 2

1

2

High-throughput

0.479

High

1154500

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1154508

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

4

Small-scale

0.479

High

1154509

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

469294

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.458

High

1154507

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1093510

TRDN
Triadin

1

3

High-throughput

0.445

High

1154513

GPC5B
G-protein coupled receptor family C group 5 member B

1

8

High-throughput

0.445

High

429957

JUN
Transcription factor Jun

1

1

High-throughput

0.437

High

695561

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

768288

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

879139

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

1099934

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

1114844

CUL4A
Cullin-4A

1

4

High-throughput

0.437

High

1154491

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1154503

SAAL1
Protein SAAL1

1

3

High-throughput

0.407

High

1154514

BCS1
Mitochondrial chaperone BCS1

1

10

High-throughput

0.407

High

1154496

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

1142548

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1154492

WDR5B
WD repeat-containing protein 5B

1

0

High-throughput

0.279

Low

1154497

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

832728

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025