HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MILK2 (Q8IY33)
MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)
Gene: MICALL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 904
+	Hs
		345805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ACTN1_HUMAN (2-218): 1.94e-67: 244: 28.57
+	Hs
		211453 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ACTN4_HUMAN (2-219): 5.5e-67: 243: 27.98
+	Hs
		346544 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SPTB2_HUMAN (2-219): 3.33e-61: 229: 30.28
+	Hs
		346268 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA4_HUMAN (316-893): 5.38e-56: 213: 12.18
+	Mm
		348422 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		SMCA4_MOUSE (316-893): 3.57e-58: 219: 12.18
+	Hs
		297710 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MICA2_HUMAN (108-777): 1.36e-19: 97.3: 15.27
+	Hs
		378964 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ACTN1_HUMAN (2-218): 1.94e-67: 244: 28.57
+	Hs
		379142 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA4_HUMAN (316-893): 5.38e-56: 213: 12.18
+	Hs
		963302 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		SPTB2_HUMAN (2-219): 3.33e-61: 229: 30.28
+	Mm
		1111973 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		SMCA4_MOUSE (316-893): 3.57e-58: 219: 12.18
+	Hs
		738948 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		SMCA4_HUMAN (316-893): 5.38e-56: 213: 12.18