HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 2048
+	Hs
		346003 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA1_HUMAN (4-1033): 8.64e-110: 379: 13.04
+	Hs
		347406 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD5_HUMAN (60-1283): 1.63e-103: 372: 12.96
+	Hs
		229271 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA5_HUMAN (4-1049): 3.79e-105: 365: 12.02
+	Hs
		348113 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD7_HUMAN (37-1421): 1.18e-99: 361: 11.19
+	Hs
		346938 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD9_HUMAN (37-1034): 1.46e-96: 351: 12.12
+	Hs
		347951 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12
+	Hs
		346805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88
+	Hs
		347538 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX58_HUMAN (90-661): 6.61e-101: 342: 17.22
+	Mm
		348432 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		CHD4_MOUSE (41-1051): 3.2e-94: 342: 11.89
+	Hs
		229276 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA5_HUMAN (4-1049): 3.79e-105: 365: 12.02
+	Hs
		379973 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD7_HUMAN (37-1421): 1.18e-99: 361: 11.19
+	Hs
		379411 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88
+	Hs
		345867 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10
+	Hs
		133814 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70
+	Hs
		347986 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX21_HUMAN (473-672): 2.66e-15: 84.1: 20.48
+	Hs
		348165 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX20_HUMAN (70-447): 1.83e-14: 81.6: 11.11
+	Mm
		348448 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		DDX20_MOUSE (22-378): 3.62e-14: 80.4: 13.23
+	Hs
		378997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10
+	Hs
		133830 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70
+	Hs
		379913 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX21_HUMAN (473-672): 2.66e-15: 84.1: 20.48