Protein: NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase)

Gene: NADC, QPRT
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q15274

Gene Ontology (top 5):
GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009435 - NAD biosynthetic process
GO:0019674 - NAD metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1070060

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

3

2

High-throughput

0.845

High

170373

TIF1A
Transcription intermediary factor 1-alpha

3

1

High-throughput

0.667

High

203374

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

3

1

High-throughput

0.667

High

941989

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

3

1

High-throughput

0.667

High

1070065

CRY1
Cryptochrome-1

3

1

High-throughput

0.667

High

1070066

CRY2
Cryptochrome-2

3

1

High-throughput

0.667

High

1070076

PATL1
Protein PAT1 homolog 1

3

1

High-throughput

0.667

High

1070106

PRC2C
Protein PRRC2C

3

2

High-throughput

0.667

High

889482

KR108
Keratin-associated protein 10-8

3

4

High-throughput

0.654

High

128857

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

3

0

High-throughput

0.638

High

182343

PER1
Period circadian protein homolog 1

3

0

High-throughput

0.638

High

212256

CIKS
E3 ubiquitin ligase TRAF3IP2

3

0

High-throughput

0.638

High

1070083

ARI1B
AT-rich interactive domain-containing protein 1B

3

0

High-throughput

0.638

High

1070093

ARP6
Actin-related protein 6

3

0

High-throughput

0.638

High

1070096

RAVR2
Ribonucleoprotein PTB-binding 2

3

0

High-throughput

0.638

High

1070075

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.613

High

321998

ZMYM6
Zinc finger MYM-type protein 6

3

1

High-throughput

0.609

High

966976

SATB1
DNA-binding protein SATB1

3

1

High-throughput

0.609

High

1070062

SF3A1
Splicing factor 3A subunit 1

3

1

High-throughput

0.609

High

1070073

BCOR
BCL-6 corepressor

3

2

High-throughput

0.609

High

1070104

TRI33
E3 ubiquitin-protein ligase TRIM33

3

1

High-throughput

0.609

High

1070105

SATB2
DNA-binding protein SATB2

3

1

High-throughput

0.609

High

991567

KRA11
Keratin-associated protein 1-1

2

4

High-throughput

0.606

High

1070086

SEH1
Nucleoporin SEH1

2

0

High-throughput

0.585

High

980755

TLE3
Transducin-like enhancer protein 3

2

3

High-throughput

0.558

High

1070085

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

2

1

High-throughput

0.558

High

1070089

KR412
Keratin-associated protein 4-12

1

4

High-throughput

0.541

High

257616

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.536

High

1070078

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

1

High-throughput

0.536

High

1070080

TENS4
Tensin-4

1

1

High-throughput

0.536

High

1070103

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.518

High

229676

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

High-throughput

0.513

High

521361

SKIL
Ski-like protein

1

0

High-throughput

0.513

High

949109

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.513

High

1070082

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.513

High

1070090

AASD1
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.513

High

1070097

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

0

High-throughput

0.513

High

1070091

NPL
N-acetylneuraminate lyase

1

0

High-throughput

0.493

High

1070069

ZMYM4
Zinc finger MYM-type protein 4

1

1

High-throughput

0.489

High

1070087

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

High-throughput

0.489

High

1070101

RCOR1
REST corepressor 1

1

2

High-throughput

0.489

High

1070107

NCOR2
Nuclear receptor corepressor 2

1

4

High-throughput

0.489

High

888876

KR103
Keratin-associated protein 10-3

1

4

High-throughput

0.481

High

1070070

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.481

High

261513

NCOR1
Nuclear receptor corepressor 1

1

3

High-throughput

0.479

High

980610

TLE1
Transducin-like enhancer protein 1

1

3

High-throughput

0.479

High

1070102

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

177301

HDAC3
Histone deacetylase 3

1

0

High-throughput

0.458

High

369649

ESR1
Estrogen receptor

1

0

High-throughput

0.458

High

890674

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

896100

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

1070068

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

1070095

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

0

Small-scale

0.458

High

1070098

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

1070100

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1070071

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

1050108

GIT2
ARF GTPase-activating protein GIT2

1

2

High-throughput

0.439

High

980934

TLE4
Transducin-like enhancer protein 4

1

3

High-throughput

0.437

High

1070067

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.437

High

1070088

MIA2
Melanoma inhibitory activity protein 2

1

1

High-throughput

0.407

High

304617

SCAF4
SR-related and CTD-associated factor 4

3

0

High-throughput

0.347

High

1018799

SF3A3
Splicing factor 3A subunit 3

3

0

High-throughput

0.347

High

1070061

SF3A2
Splicing factor 3A subunit 2

3

0

High-throughput

0.347

High

1070064

VPS72
Vacuolar protein sorting-associated protein 72 homolog

3

0

High-throughput

0.347

High

1070074

SRCAP
Helicase SRCAP

3

0

High-throughput

0.347

High

1070077

I2BP1
Interferon regulatory factor 2-binding protein 1

3

0

High-throughput

0.347

High

1070092

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

3

0

High-throughput

0.347

High

1070094

ADNP
Activity-dependent neuroprotector homeobox protein

3

0

High-throughput

0.347

High

1070084

P66B
Transcriptional repressor p66-beta

2

0

High-throughput

0.328

High

1070072

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1070099

NLGN3
Neuroligin-3

1

0

Small-scale

0.299

High

165485

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.279

Low

1055278

GBX1
Homeobox protein GBX-1

1

0

High-throughput

0.279

Low

1070063

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

0

High-throughput

0.279

Low

1070081

MPND
MPN domain-containing protein

1

0

High-throughput

0.279

Low

1070079

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024