HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DDX1 (Q92499)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)
Gene: DDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	29467282, 35013218, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 740
+	Hs
		379665 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX1_HUMAN (1-740): 0: 573: 100.00
+	Hs
		133814 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		347494 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		345867 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96
+	Hs
		348064 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX43_HUMAN (285-626): 3.03e-34: 141: 29.75
+	Hs
		346115 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF4A3_HUMAN (3-72): 3.92e-11: 67.8: 30.00
+	Hs
		133830 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		379679 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX17_HUMAN (1-381): 4.07e-36: 147: 12.21
+	Hs
		378997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96
+	Hs
		379085 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF4A3_HUMAN (3-72): 3.92e-11: 67.8: 30.00