HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ZN106 (Q9H2Y7)
Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474)
Gene: ZNF106

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36424410, 21150319
Identification Methods	proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 1883
+	Hs
		379857 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ZN106_HUMAN (1-1883): 0: 2397: 100.00
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (1602-1882): 1.34e-86: 301: 19.79
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (1602-1882): 6.1e-86: 299: 19.79
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (1369-1728): 1.14e-73: 254: 14.61
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (1692-1883): 1.07e-58: 208: 15.00
+	Hs
		196936 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP4_HUMAN (1641-1883): 3.02e-48: 183: 16.22
+	Hs
		347178 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		KI21A_HUMAN (1607-1882): 7.99e-42: 171: 12.34
+	Hs
		348277 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBW1A_HUMAN (1471-1645): 2.02e-35: 146: 16.06
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (1602-1882): 1.34e-86: 301: 19.79
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (1323-1525): 9.65e-16: 84.4: 7.88
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (1602-1882): 6.1e-86: 299: 19.79
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (1602-1882): 6.1e-86: 299: 19.79
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (1602-1882): 1.34e-86: 301: 19.79
+	Dm
		1375911 MYC_DROME (210-454): 3.25e-30: 126: 26.74		FBXW7_DROME (1610-1882): 1.83e-77: 285: 19.78
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (1692-1883): 1.07e-58: 208: 15.00
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (1692-1883): 1.07e-58: 208: 15.00
+	Hs
		253245 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		KI21B_HUMAN (1607-1882): 2.55e-45: 183: 13.57
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (1692-1883): 1.07e-58: 208: 15.00
+	Hs
		252935 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		FBW1B_HUMAN (1488-1641): 3.1e-36: 148: 17.44
+	Hs
		252937 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		FBW1A_HUMAN (1471-1645): 2.02e-35: 146: 16.06