Protein: UPK2
Uroplakin-2 (UP2) (Uroplakin II) (UPII)

Gene: UPK2
Organism: Homo sapiens
Interactions: 144
UniProt ID: O00526

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0030855 - epithelial cell differentiation
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

131851

TNF11
Tumor necrosis factor ligand superfamily member 11

2

1

High-throughput

0.606

High

131853

TMPS2
Transmembrane protease serine 2

2

2

High-throughput

0.606

High

131854

TNF14
Tumor necrosis factor ligand superfamily member 14

2

1

High-throughput

0.606

High

131866

HEPS
Serine protease hepsin

2

2

High-throughput

0.606

High

131867

ASGR2
Asialoglycoprotein receptor 2

2

2

High-throughput

0.606

High

131870

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

2

High-throughput

0.606

High

131871

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

2

2

High-throughput

0.606

High

131881

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

2

High-throughput

0.606

High

131924

AGRG3
Adhesion G protein-coupled receptor G3

2

5

High-throughput

0.606

High

131928

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

2

2

High-throughput

0.606

High

131953

CLC7A
C-type lectin domain family 7 member A

2

2

High-throughput

0.606

High

49720

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.580

High

131857

RENR
Renin receptor

2

0

High-throughput

0.580

High

131862

CLD7
Claudin-7

2

0

High-throughput

0.580

High

131864

HG2A
HLA class II histocompatibility antigen gamma chain

2

0

High-throughput

0.580

High

131889

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.580

High

131894

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

131902

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

131915

BTNL9
Butyrophilin-like protein 9

2

0

High-throughput

0.580

High

131931

STML3
Stomatin-like protein 3

2

0

High-throughput

0.580

High

131948

GPA33
Cell surface A33 antigen

2

0

High-throughput

0.580

High

131973

ITM2C
Integral membrane protein 2C

2

0

High-throughput

0.580

High

131888

FCGRN
IgG receptor FcRn large subunit p51

2

3

High-throughput

0.553

High

131916

CL17A
C-type lectin domain family 17, member A

2

2

High-throughput

0.553

High

131860

AGRL1
Adhesion G protein-coupled receptor L1

1

5

High-throughput

0.536

High

131868

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.536

High

131872

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.536

High

131873

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

1

High-throughput

0.536

High

131875

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

2

High-throughput

0.536

High

131882

AGRE5
Adhesion G protein-coupled receptor E5

1

5

High-throughput

0.536

High

131883

BCAM
Basal cell adhesion molecule

1

2

High-throughput

0.536

High

131886

AT12A
Potassium-transporting ATPase alpha chain 2

1

2

High-throughput

0.536

High

131892

PCDH1
Protocadherin-1

1

4

High-throughput

0.536

High

131895

CD166
CD166 antigen

1

2

High-throughput

0.536

High

131899

PRSS8
Prostasin

1

2

High-throughput

0.536

High

131904

AGRF1
Adhesion G-protein coupled receptor F1

1

5

High-throughput

0.536

High

131909

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

2

High-throughput

0.536

High

131913

CNNM4
Metal transporter CNNM4

1

1

High-throughput

0.536

High

131917

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.536

High

131920

MON2
Protein MON2 homolog

1

3

High-throughput

0.536

High

131921

AGRG6
Adhesion G-protein coupled receptor G6

1

5

High-throughput

0.536

High

131967

CNNM2
Metal transporter CNNM2

1

1

High-throughput

0.536

High

131969

PCDH9
Protocadherin-9

1

5

High-throughput

0.536

High

131970

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

2

High-throughput

0.536

High

131976

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

1

High-throughput

0.536

High

131977

PCD10
Protocadherin-10

1

2

High-throughput

0.536

High

131982

PCDB2
Protocadherin beta-2

1

2

High-throughput

0.536

High

131983

PCDGB
Protocadherin gamma-A11

1

1

High-throughput

0.536

High

58770

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

131856

NRP2
Neuropilin-2

1

0

High-throughput

0.513

High

131861

UCP5
Brain mitochondrial carrier protein 1

1

0

High-throughput

0.513

High

131878

IL6RB
Interleukin-6 receptor subunit beta

1

0

High-throughput

0.513

High

131879

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

131880

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

131884

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.513

High

131890

ASIC1
Acid-sensing ion channel 1

1

0

High-throughput

0.513

High

131893

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.513

High

131896

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.513

High

131898

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

1

0

High-throughput

0.513

High

131900

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.513

High

131906

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

0

High-throughput

0.513

High

131911

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

0

High-throughput

0.513

High

131919

SV2A
Synaptic vesicle glycoprotein 2A

1

0

High-throughput

0.513

High

131929

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

131930

NLGN2
Neuroligin-2

1

0

High-throughput

0.513

High

131932

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

131934

MOT10
Monocarboxylate transporter 10

1

0

High-throughput

0.513

High

131935

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

131943

KIRR1
Kin of IRRE-like protein 1

1

0

High-throughput

0.513

High

131947

SORT
Sortilin

1

0

High-throughput

0.513

High

131954

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

131956

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

131957

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

131959

SEM4C
Semaphorin-4C

1

0

High-throughput

0.513

High

131962

F234A
Protein FAM234A

1

0

High-throughput

0.513

High

131965

ANTR1
Anthrax toxin receptor 1

1

0

High-throughput

0.513

High

131968

RHOF
Rho-related GTP-binding protein RhoF

1

0

High-throughput

0.513

High

131972

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

131979

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.513

High

131981

LRP12
Low-density lipoprotein receptor-related protein 12

1

0

High-throughput

0.513

High

131984

BACE2
Beta-secretase 2

1

0

High-throughput

0.513

High

131852

TM9S1
Transmembrane 9 superfamily member 1

1

2

High-throughput

0.489

High

131855

XPOT
Exportin-T

1

1

High-throughput

0.489

High

131858

C1QRF
C1q-related factor

1

1

High-throughput

0.489

High

131859

IPO13
Importin-13

1

1

High-throughput

0.489

High

131925

C1QL4
Complement C1q-like protein 4

1

1

High-throughput

0.489

High

131937

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.489

High

131938

TM9S4
Transmembrane 9 superfamily member 4

1

2

High-throughput

0.489

High

131939

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

2

High-throughput

0.489

High

131949

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.489

High

131950

CSTN3
Calsyntenin-3

1

2

High-throughput

0.489

High

131966

AT133
Polyamine-transporting ATPase 13A3

1

3

High-throughput

0.489

High

131971

TM9S3
Transmembrane 9 superfamily member 3

1

2

High-throughput

0.489

High

131987

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

3

High-throughput

0.489

High

131988

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

3

High-throughput

0.489

High

131850

UPK2
Uroplakin-2

1

0

Small-scale

0.480

High

111306

J3KQ12
Seipin

1

1

High-throughput

0.470

High

125941

UPK1A
Uroplakin-1a

1

0

Small-scale

0.458

High

131865

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

2

High-throughput

0.445

High

131941

BSCL2
Seipin

1

1

High-throughput

0.439

High

131923

AMGO1
Amphoterin-induced protein 1

2

0

High-throughput

0.316

High

131933

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

131936

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.316

High

131944

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.316

High

131952

T106C
Transmembrane protein 106C

2

0

High-throughput

0.316

High

131963

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

131927

KASH5
Protein KASH5

1

0

High-throughput

0.299

High

131874

CTNA2
Catenin alpha-2

1

0

High-throughput

0.279

Low

131876

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

131877

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.279

Low

131891

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

131897

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

131901

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

0

High-throughput

0.279

Low

131903

MKS3
Meckelin

1

0

High-throughput

0.279

Low

131905

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

131907

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.279

Low

131908

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

131910

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

131912

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.279

Low

131914

INT5
Integrator complex subunit 5

1

0

High-throughput

0.279

Low

131918

INT8
Integrator complex subunit 8

1

0

High-throughput

0.279

Low

131922

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

131926

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.279

Low

131940

GLT14
Polypeptide N-acetylgalactosaminyltransferase 14

1

0

High-throughput

0.279

Low

131942

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

131945

ARL5B
ADP-ribosylation factor-like protein 5B

1

0

High-throughput

0.279

Low

131946

GCP5
Gamma-tubulin complex component 5

1

0

High-throughput

0.279

Low

131951

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.279

Low

131955

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

131958

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

High-throughput

0.279

Low

131960

INT2
Integrator complex subunit 2

1

0

High-throughput

0.279

Low

131961

LMA2L
VIP36-like protein

1

0

High-throughput

0.279

Low

131964

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

131974

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low

131975

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.279

Low

131978

IPO11
Importin-11

1

0

High-throughput

0.279

Low

131980

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.279

Low

131985

ORNT1
Mitochondrial ornithine transporter 1

1

0

High-throughput

0.279

Low

131863

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.251

Low

131885

VMAT1
Chromaffin granule amine transporter

1

0

High-throughput

0.251

Low

131986

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.251

Low

131869

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.249

Low

131887

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024