HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MDN1 (Q9NU22)
Midasin (Dynein-related AAA-ATPase MDN1) (MIDAS-containing protein)
Gene: MDN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 36424410, 17353931
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 5596
+	Hs
		346767 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DYHC1_HUMAN (802-2223): 6.07e-143: 508: 13.58
+	Dm
		1182653 Q9W4Q7_DROME (358-449): 5.64e-19: 91.7: 29.03		Q7KVA7_DROME (956-2246): 8.61e-164: 577: 12.75
+	Hs
		898121 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		DYHC1_HUMAN (802-2223): 6.07e-143: 508: 13.58
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (4403-5388): 1.78e-29: 133: 10.48
+	Hs
		347374 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		BD1L1_HUMAN (4818-5348): 1.21e-16: 90.7: 11.11
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (4414-5112): 2.34e-16: 90: 10.92
+	Hs
		346210 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NEST_HUMAN (4395-5330): 7.17e-15: 84.9: 13.06
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (4810-5327): 5.69e-14: 81.9: 9.46
+	Hs
		346499 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1A_HUMAN (4766-5318): 2.21e-10: 70.2: 13.56
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (4403-5388): 1.78e-29: 133: 10.48
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (4810-5327): 5.69e-14: 81.9: 9.46