HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	29467282, 30415952, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 670
+	Hs
		346685 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Hs
		347382 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX55_HUMAN (176-668): 5.77e-136: 413: 34.05
+	Hs
		347494 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		345867 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		133814 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		348064 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX43_HUMAN (23-583): 9.3e-124: 383: 25.44
+	Hs
		379930 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX18_HUMAN (1-670): 5.81e-174: 513: 100.00
+	Hs
		379357 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Hs
		347913 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		379634 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX55_HUMAN (176-668): 5.77e-136: 413: 34.05
+	Hs
		379679 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX17_HUMAN (99-603): 5.5e-134: 412: 24.95
+	Hs
		378997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX5_HUMAN (71-600): 2.27e-133: 407: 22.47
+	Hs
		133830 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Hs
		347859 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX47_HUMAN (192-524): 3.3e-64: 221: 39.82
+	Hs
		347584 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Hs
		348398 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX49_HUMAN (195-565): 1.87e-54: 195: 33.95
+	Hs
		379875 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		379851 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX47_HUMAN (192-524): 3.3e-64: 221: 39.82
+	Hs
		379724 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88