HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35013218, 17314511
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0010468 - regulation of gene expression
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 577
+	Hs
		127974 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		127979 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		379960 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		346847 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		348394 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		347594 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		347530 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		347503 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		346846 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		346354 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP3_HUMAN (65-270): 1.9e-09: 61.5: 15.31
+	Hs
		379429 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		380081 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		379728 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		379692 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		379683 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		379428 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		379180 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP3_HUMAN (65-270): 1.9e-09: 61.5: 15.31