HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DDX52 (Q9Y2R4)
Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52)
Gene: DDX52

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	29467282, 30415952, 36424410, 17314511
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 599
+	Hs
		347494 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX17_HUMAN (103-599): 1.01e-140: 427: 25.30
+	Hs
		133814 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX3X_HUMAN (1-546): 2.47e-141: 426: 25.88
+	Hs
		345867 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX5_HUMAN (86-598): 4.37e-140: 421: 24.52
+	Hs
		347225 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX42_HUMAN (5-546): 2.97e-128: 401: 25.31
+	Hs
		348064 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX43_HUMAN (1-574): 1.76e-128: 393: 25.50
+	Hs
		379540 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX46_HUMAN (36-593): 1.86e-167: 505: 28.52
+	Hs
		380037 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX52_HUMAN (1-599): 1.16e-158: 469: 100.00
+	Hs
		379679 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX17_HUMAN (103-599): 1.01e-140: 427: 25.30
+	Hs
		133830 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX3X_HUMAN (1-546): 2.47e-141: 426: 25.88
+	Hs
		378997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX5_HUMAN (86-598): 4.37e-140: 421: 24.52
+	Hs
		379911 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX4_HUMAN (149-543): 1.09e-57: 207: 33.83