HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~Ras
Common GO terms	GO:0000165 - MAPK cascade GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 781
+	Hs
		717259 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		349923 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717100 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		349154 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		716953 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542399 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		349846 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542331 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		542267 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Hs
		119749 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ARVC_HUMAN (202-771): 5.66e-94: 316: 18.66
+	Hs
		119748 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ARVC_HUMAN (202-771): 5.66e-94: 316: 18.66
+	Hs
		349993 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		IMA1_HUMAN (237-675): 3.54e-66: 231: 18.54