HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: SC6A8 (P48029)
Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)
Gene: SLC6A8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 635
+	Hs
		349966 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SC6A8_HUMAN (1-621): 0: 733: 100.00
+	Hs
		815776 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		SC6A8_HUMAN (1-621): 0: 733: 100.00
+	Hs
		815764 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SC6A8_HUMAN (1-621): 0: 733: 100.00
+	Hs
		815760 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		SC6A8_HUMAN (1-621): 0: 733: 100.00
+	Hs
		1070470 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		SC6A5_HUMAN (38-623): 0: 702: 41.31
+	Hs
		349915 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SC6A6_HUMAN (22-635): 0: 692: 53.82
+	Hs
		348535 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		SC6A6_HUMAN (22-635): 0: 692: 53.82
+	Hs
		681196 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		SC6A6_HUMAN (22-635): 0: 692: 53.82
+	Hs
		349967 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SC6A9_HUMAN (41-624): 0: 653: 42.42
+	Hs
		348566 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		SC6A9_HUMAN (41-624): 0: 653: 42.42
+	Hs
		349182 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SC6A9_HUMAN (41-624): 0: 653: 42.42
+	Rn
		621439 RIT2_RAT (3-165): 2.53e-55: 176: 53.05		SC6A3_RAT (40-597): 0: 668: 43.75
+	Hs
		350541 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		1070390 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		348918 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		918947 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		914352 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		895268 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		S6A15_HUMAN (34-579): 0: 554: 32.64
+	Hs
		896684 RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35		S6A15_HUMAN (34-579): 0: 554: 32.64