HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 671
+	Hs
		1273004 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		350438 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		894790 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		349554 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914274 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914240 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SYTL5_HUMAN (2-669): 9.15e-161: 481: 38.17
+	Hs
		894765 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		SYTL1_HUMAN (110-665): 1.09e-83: 276: 29.62
+	Hs
		1134943 RAB1B_HUMAN (4-187): 1.35e-75: 226: 33.51		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		896633 RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		897901 RAP1B_HUMAN (1-165): 1.02e-61: 191: 56.89		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		207683 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		1273014 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		RP3A_HUMAN (518-671): 1.14e-28: 123: 23.08
+	Hs
		894828 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RP3A_HUMAN (518-671): 1.14e-28: 123: 23.08
+	Hs
		207682 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		129082 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		SYT5_HUMAN (347-458): 3.13e-19: 92.2: 31.25