Protein: CLIC3
Chloride intracellular channel protein 3 (Glutaredoxin-like oxidoreductase CLIC3) (EC 1.8.-.-)

Gene: CLIC3
Organism: Homo sapiens
Interactions: 58
UniProt ID: O95833

Gene Ontology (top 5):
GO:0005254 - chloride channel activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006821 - chloride transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

348873

PRSR2
Proline and serine-rich protein 2

3

1

High-throughput

0.607

High

74326

ZBT42
Zinc finger and BTB domain-containing protein 42

2

1

High-throughput

0.606

High

348852

MSX2
Homeobox protein MSX-2

2

1

High-throughput

0.606

High

348855

MECOM
Histone-lysine N-methyltransferase MECOM

2

2

High-throughput

0.606

High

348857

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

348867

TGO1
Transport and Golgi organization protein 1 homolog

2

1

High-throughput

0.606

High

348870

ZN620
Zinc finger protein 620

2

1

High-throughput

0.606

High

348872

ANR23
Ankyrin repeat domain-containing protein 23

2

1

High-throughput

0.606

High

348894

VPS4A
Vacuolar protein sorting-associated protein 4A

2

4

High-throughput

0.606

High

348890

PCD12
Protocadherin-12

2

0

High-throughput

0.602

High

348844

AGR2
Anterior gradient protein 2 homolog

3

2

High-throughput

0.596

High

348856

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

348859

ALX1
ALX homeobox protein 1

2

0

High-throughput

0.580

High

348875

SCML4
Sex comb on midleg-like protein 4

2

0

High-throughput

0.580

High

348876

SMIP4
Sperm-associated microtubule inner protein 4

2

0

High-throughput

0.580

High

348878

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.580

High

348881

MB3L1
Methyl-CpG-binding domain protein 3-like 1

2

0

High-throughput

0.580

High

348883

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

348884

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

348889

KTBL1
KATNB1-like protein 1

2

0

High-throughput

0.580

High

348893

STMN3
Stathmin-3

2

0

High-throughput

0.580

High

348868

EFHC2
EF-hand domain-containing family member C2

2

1

High-throughput

0.573

High

348863

GLYR1
Cytokine-like nuclear factor N-PAC

2

2

High-throughput

0.553

High

348849

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

348858

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

10

High-throughput

0.536

High

348866

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

2

High-throughput

0.536

High

348885

MIA2
Melanoma inhibitory activity protein 2

1

4

High-throughput

0.536

High

65206

TBC3F
TBC1 domain family member 3F

1

1

High-throughput

0.515

High

340553

CNOT4
CCR4-NOT transcription complex subunit 4

1

0

High-throughput

0.513

High

348851

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

348853

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

348864

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.513

High

348874

OCAT1
POU domain class 2-associating factor 2

1

0

High-throughput

0.513

High

348877

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

348879

CBPC3
Cytosolic carboxypeptidase 3

1

0

High-throughput

0.513

High

348886

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

348887

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

1

0

High-throughput

0.513

High

348891

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

348895

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

348847

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

348845

IL1A
Interleukin-1 alpha

1

0

High-throughput

0.493

High

348850

RFX1
MHC class II regulatory factor RFX1

1

1

High-throughput

0.489

High

348871

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.489

High

805

TBC3K
TBC1 domain family member 3K

1

1

High-throughput

0.481

High

348846

ESR1
Estrogen receptor

1

3

High-throughput

0.479

High

348880

MK15
Mitogen-activated protein kinase 15

1

4

Small-scale

0.479

High

261032

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

348888

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.426

High

70914

CMI2B
Ciliary microtubule inner protein 2B

2

0

High-throughput

0.316

High

348854

KRT85
Keratin, type II cuticular Hb5

2

0

High-throughput

0.316

High

348861

ANR55
Ankyrin repeat domain-containing protein 55

2

0

High-throughput

0.316

High

348862

KR133
Keratin-associated protein 13-3

2

0

High-throughput

0.316

High

348865

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

348869

LELP1
Late cornified envelope-like proline-rich protein 1

2

0

High-throughput

0.316

High

348892

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.299

High

348860

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

348882

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

348848

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025