HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: RAB23 (Q9ULC3)
Ras-related protein Rab-23
Gene: RAB23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 237
+	Hs
		350037 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		894715 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RAB1A_HUMAN (2-201): 1.02e-86: 257: 30.35
+	Hs
		1273009 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		RAB1B_HUMAN (2-201): 1.76e-85: 254: 31.34
+	Mm
		918986 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB1A_MOUSE (2-201): 1.02e-86: 257: 30.35
+	Hs
		350670 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RAB23_HUMAN (1-237): 1.39e-84: 253: 100.00
+	Hs
		894787 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		RAB8A_HUMAN (2-200): 9.67e-84: 249: 29.50
+	Hs
		350033 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Hs
		894712 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RB11A_HUMAN (3-210): 2.35e-83: 249: 29.67
+	Mm
		895595 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB8B_MOUSE (2-200): 8.39e-84: 250: 30.50
+	Hs
		894709 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RAB10_HUMAN (1-209): 7.43e-83: 247: 30.48
+	Mm
		877193 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB8A_MOUSE (2-200): 6.47e-83: 247: 30.50
+	Mm
		895579 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB10_MOUSE (1-209): 7.43e-83: 247: 30.48
+	Hs
		591536 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RAB3B_HUMAN (3-189): 3.84e-37: 131: 33.51
+	Mm
		926076 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB3A_MOUSE (3-184): 2.55e-36: 129: 35.33
+	Mm
		722682 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		RAB3D_MOUSE (3-190): 1.57e-35: 127: 33.86
+	Hs
		845875 RAB8B_HUMAN (4-181): 2.25e-85: 251: 36.11		RAB13_HUMAN (11-172): 4.05e-34: 123: 37.42
+	Hs
		349985 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RAB13_HUMAN (11-172): 4.05e-34: 123: 37.42
+	Hs
		845844 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		RAB13_HUMAN (11-172): 4.05e-34: 123: 37.42
+	Hs
		349984 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RAB7A_HUMAN (7-172): 2.64e-33: 121: 35.47