HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30442766
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1085
+	Hs
		350688 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S12A4_HUMAN (1-1085): 0: 1180: 100.00
+	Hs
		1070458 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S12A4_HUMAN (1-1085): 0: 1180: 100.00
+	Hs
		350657 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S12A6_HUMAN (7-1085): 0: 1111: 76.53
+	Hs
		350738 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		1070484 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		349035 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		350004 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		873920 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		348593 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		349996 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		854884 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		348588 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTR2_HUMAN (161-603): 2.22e-92: 311: 15.54
+	Hs
		349913 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		676544 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		348533 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		350407 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		YLAT2_HUMAN (162-661): 2.93e-81: 276: 11.91
+	Hs
		349149 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		CTR1_HUMAN (162-603): 1.06e-84: 289: 12.61
+	Hs
		350085 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65
+	Hs
		966066 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65
+	Hs
		348622 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		LAT1_HUMAN (162-687): 1.61e-79: 271: 13.65