HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: RAB6A (P20340)
Ras-related protein Rab-6A (Rab-6)
Gene: RAB6A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005789 - endoplasmic reticulum membrane GO:0005794 - Golgi apparatus and 2 others more... GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 208
+	Hs
		348601 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RAB1A_HUMAN (1-207): 2.16e-92: 270: 35.27
+	Hs
		348506 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RAB6A_HUMAN (1-208): 2.17e-89: 263: 100.00
+	Hs
		350037 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAB1A_HUMAN (1-207): 2.16e-92: 270: 35.27
+	Hs
		349871 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAB6A_HUMAN (1-208): 2.17e-89: 263: 100.00
+	Hs
		348682 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RB11B_HUMAN (3-208): 7.68e-85: 252: 29.77
+	Zm
		73944 B4FAE1_MAIZE (4-187): 6.22e-79: 235: 33.67		B4FAE1_MAIZE (9-207): 2.5e-93: 272: 35.18
+	Hs
		350033 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58
+	Hs
		350197 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RB11B_HUMAN (3-208): 7.68e-85: 252: 29.77
+	Hs
		918846 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB1A_HUMAN (1-207): 2.16e-92: 270: 35.27
+	Hs
		844470 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB5C_HUMAN (3-207): 7.83e-91: 266: 39.51
+	Hs
		844468 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		RAB5C_HUMAN (3-207): 7.83e-91: 266: 39.51
+	Hs
		918944 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB1B_HUMAN (9-206): 1.18e-89: 263: 35.86
+	Mm
		919000 RAB1A_MOUSE (4-186): 2.67e-75: 226: 31.28		RAB1B_MOUSE (9-206): 1.18e-89: 263: 36.87
+	Hs
		592649 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		RAB6A_HUMAN (1-208): 2.17e-89: 263: 100.00
+	Hs
		913992 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58
+	Hs
		913989 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58
+	Hs
		918879 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RB11B_HUMAN (3-208): 7.68e-85: 252: 29.77
+	Hs
		914093 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		RB11B_HUMAN (3-208): 7.68e-85: 252: 29.77