HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: NECT1 (Q15223)
Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)
Gene: NECTIN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 517
+	Hs
		348671 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT1_HUMAN (1-517): 2.58e-113: 347: 100.00
+	Hs
		350183 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT1_HUMAN (1-517): 2.58e-113: 347: 100.00
+	Hs
		348836 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		350416 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		350513 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CADM1_HUMAN (19-394): 1.45e-68: 228: 19.02
+	Hs
		348943 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT3_HUMAN (24-517): 1.69e-62: 215: 29.03
+	Hs
		350584 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT3_HUMAN (24-517): 1.69e-62: 215: 29.03
+	Hs
		914262 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NECT2_HUMAN (27-406): 1.14e-69: 234: 31.82
+	Hs
		348808 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CADM4_HUMAN (34-404): 1.98e-55: 192: 19.58
+	Hs
		348841 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NEO1_HUMAN (28-498): 1.77e-43: 167: 14.49
+	Hs
		350424 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NEO1_HUMAN (28-498): 1.77e-43: 167: 14.49
+	Hs
		348867 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KIRR1_HUMAN (29-489): 3.31e-35: 141: 13.74
+	Hs
		350455 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KIRR1_HUMAN (29-489): 3.31e-35: 141: 13.74
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (20-508): 1.25e-29: 125: 10.69
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (20-508): 1.25e-29: 125: 10.69
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (235-517): 7.1e-25: 111: 12.95
+	Hs
		348489 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NCAM1_HUMAN (28-360): 1.99e-20: 97.1: 13.41
+	Hs
		349841 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NCAM1_HUMAN (28-360): 1.99e-20: 97.1: 13.41
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (154-516): 9.68e-09: 60.5: 8.27
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (154-516): 9.68e-09: 60.5: 8.27