HitPredict

Interactor 1: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26355680
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras, Ras~Roc
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0030672 - synaptic vesicle membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 2527
+	Hs
		72911 B4DMN1_HUMAN (1-218): 1.04e-91: 271: 90.37		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		914117 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130165 Q5U0I6_HUMAN (1-215): 2.92e-90: 265: 43.26		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		918884 RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130572 RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	At
		656926 RAA5C_ARATH (5-195): 2.25e-74: 225: 59.59		CRK10_ARATH (1850-2134): 6.12e-85: 296: 28.80
+	At
		955322 RAB1C_ARATH (7-215): 3.29e-85: 252: 45.46		BRL2_ARATH (1470-1771): 1.68e-09: 65.8: 10.33