HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 671
+	Hs
		348852 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		350438 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914274 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		1273004 RAB8B_HUMAN (4-180): 8.57e-74: 222: 36.31		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		914240 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		SYTL5_HUMAN (2-669): 9.15e-161: 481: 38.17
+	Hs
		1134943 RAB1B_HUMAN (4-186): 2.6e-74: 223: 31.44		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		897901 RAP1B_HUMAN (1-165): 2.18e-63: 195: 57.49		SYT6_HUMAN (224-660): 2.2e-85: 279: 21.56
+	Hs
		207683 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		207682 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		SYT7_HUMAN (509-664): 8.34e-33: 132: 29.49
+	Hs
		1273014 RAB8B_HUMAN (4-180): 8.57e-74: 222: 36.31		RP3A_HUMAN (518-671): 1.14e-28: 123: 23.08
+	Hs
		129082 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		SYT5_HUMAN (347-458): 3.13e-19: 92.2: 31.25