HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: RAP2C (Q9Y3L5)
Ras-related protein Rap-2c (EC 3.6.5.2)
Gene: RAP2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 2 others more... GO:0005886 - plasma membrane GO:0019003 - GDP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 183
+	Hs
		349024 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RAP2C_HUMAN (1-183): 6.64e-85: 249: 100.00
+	Hs
		350718 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAP2C_HUMAN (1-183): 6.64e-85: 249: 100.00
+	Hs
		350038 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAP1A_HUMAN (1-182): 6.66e-82: 242: 61.75
+	Hs
		348601 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RAB1A_HUMAN (4-170): 1.34e-76: 229: 35.71
+	Hs
		350037 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAB1A_HUMAN (4-170): 1.34e-76: 229: 35.71
+	Hs
		348578 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RAB13_HUMAN (4-179): 1.04e-72: 219: 32.20
+	Zm
		73944 B4FAE1_MAIZE (4-187): 6.22e-79: 235: 33.67		B4FAE1_MAIZE (4-183): 6.42e-80: 237: 34.62
+	Hs
		349985 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAB13_HUMAN (4-179): 1.04e-72: 219: 32.20
+	Hs
		350016 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RAB14_HUMAN (4-183): 1.1e-72: 219: 30.39
+	Hs
		350033 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RB11A_HUMAN (4-177): 1.26e-72: 219: 29.71
+	Hs
		918846 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB1A_HUMAN (4-170): 1.34e-76: 229: 35.71
+	Hs
		918944 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB1B_HUMAN (4-179): 2.04e-76: 228: 33.33
+	Mm
		919000 RAB1A_MOUSE (4-186): 2.67e-75: 226: 31.28		RAB1B_MOUSE (4-179): 5.33e-76: 227: 33.33
+	Hs
		896605 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RAB14_HUMAN (4-183): 1.1e-72: 219: 30.39
+	Hs
		913992 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		RB11A_HUMAN (4-177): 1.26e-72: 219: 29.71
+	Mm
		1321974 RAB1B_MOUSE (4-185): 1.54e-74: 224: 30.93		RAB13_MOUSE (4-181): 3.81e-73: 220: 30.73
+	Hs
		845845 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		RAB13_HUMAN (4-179): 1.04e-72: 219: 32.20
+	Hs
		348486 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		RALA_HUMAN (4-164): 1.06e-47: 155: 45.96
+	Hs
		349831 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		RALA_HUMAN (4-164): 1.06e-47: 155: 45.96