Protein: ZKSC1
Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)

Gene: ZKSC1, ZKSCAN1
Organism: Homo sapiens
Interactions: 71
UniProt ID: P17029

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600447

ZSC32
Zinc finger and SCAN domain-containing protein 32

5

19

High-throughput

0.932

High

600431

ZN397
Zinc finger protein 397

4

20

High-throughput

0.892

High

600402

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

20

High-throughput

0.861

High

600247

ZNF24
Zinc finger protein 24

3

20

High-throughput

0.855

High

600434

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

3

19

High-throughput

0.855

High

600432

ZN483
Zinc finger protein 483

2

19

High-throughput

0.811

High

600455

ZN232
Zinc finger protein 232

2

20

High-throughput

0.811

High

600412

MK07
Mitogen-activated protein kinase 7

2

1

High-throughput

0.783

High

600446

ZN446
Zinc finger protein 446

2

18

High-throughput

0.776

High

600457

ZSC21
Zinc finger and SCAN domain-containing protein 21

2

20

High-throughput

0.776

High

600415

KGP1
cGMP-dependent protein kinase 1

2

1

High-throughput

0.726

High

163489

ZN213
Zinc finger protein 213

1

19

High-throughput

0.691

High

600403

MZF1
Myeloid zinc finger 1

1

18

High-throughput

0.691

High

600406

SCND1
SCAN domain-containing protein 1

1

18

High-throughput

0.691

High

600419

ZN174
Zinc finger protein 174

1

18

High-throughput

0.691

High

600421

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

19

High-throughput

0.691

High

600422

ZSC23
Zinc finger and SCAN domain-containing protein 23

1

20

High-throughput

0.691

High

600428

ZN444
Zinc finger protein 444

1

20

High-throughput

0.691

High

600437

PGBD1
PiggyBac transposable element-derived protein 1

1

18

High-throughput

0.691

High

600425

RFPLB
Ret finger protein-like 4B

3

20

High-throughput

0.667

High

385427

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

20

High-throughput

0.650

High

339647

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.646

High

600407

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.638

High

600418

OZF
Zinc finger protein OZF

1

20

High-throughput

0.618

High

189405

STX7
Syntaxin-7

3

3

High-throughput

0.609

High

600427

STX12
Syntaxin-12

3

3

High-throughput

0.609

High

600438

ZN396
Zinc finger protein 396

1

20

High-throughput

0.575

High

355063

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

2

9

High-throughput

0.574

High

600449

CEP72
Centrosomal protein of 72 kDa

2

1

High-throughput

0.574

High

395443

ESR1
Estrogen receptor

2

13

High-throughput

0.571

High

600410

NOTC2
Neurogenic locus notch homolog protein 2

1

17

High-throughput

0.536

High

600429

ZCHC7
Zinc finger CCHC domain-containing protein 7

1

5

High-throughput

0.536

High

600430

TEX19
Testis-expressed protein 19

1

1

High-throughput

0.536

High

600444

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.536

High

600456

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

1

High-throughput

0.536

High

600405

MATR3
Matrin-3

1

1

High-throughput

0.515

High

600435

OPTN
Optineurin

1

4

High-throughput

0.515

High

600416

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.489

High

600436

VWCE
von Willebrand factor C and EGF domain-containing protein

1

20

High-throughput

0.489

High

600445

TNR19
Tumor necrosis factor receptor superfamily member 19

1

2

High-throughput

0.489

High

240680

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

600404

MTOR
Serine/threonine-protein kinase mTOR

1

1

Small-scale

0.479

High

600408

RNF4
E3 ubiquitin-protein ligase RNF4

1

13

High-throughput

0.479

High

600411

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

3

High-throughput

0.479

High

600413

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.479

High

600414

CUL3
Cullin-3

1

20

High-throughput

0.479

High

600417

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

600433

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

600441

PCGF6
Polycomb group RING finger protein 6

1

4

High-throughput

0.479

High

600442

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.479

High

600450

ZMYM2
Zinc finger MYM-type protein 2

1

14

High-throughput

0.479

High

600452

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

600453

XPO7
Exportin-7

1

7

High-throughput

0.479

High

600454

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.479

High

600409

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

600420

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.458

High

421452

A4
Amyloid-beta precursor protein

1

14

High-throughput

0.457

High

600423

CAVN1
Caveolae-associated protein 1

1

2

High-throughput

0.445

High

600443

TGIF2
Homeobox protein TGIF2

1

5

High-throughput

0.445

High

600448

GRHL1
Grainyhead-like protein 1 homolog

1

2

High-throughput

0.445

High

105276

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

174920

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.437

High

293163

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

411308

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

600426

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

387094

TNNC2
Troponin C, skeletal muscle

1

1

High-throughput

0.407

High

600424

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.407

High

600451

SL9A2
Sodium/hydrogen exchanger 2

1

8

High-throughput

0.407

High

289844

TIPRL
TIP41-like protein

1

0

High-throughput

0.249

Low

600439

PELO
Protein pelota homolog

1

0

High-throughput

0.249

Low

600440

CP250
Centrosome-associated protein CEP250

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025