HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: JAM1 (Q9Y624)
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Gene: F11R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 299
+	Hs
		349034 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		350737 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		348900 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		350505 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		348608 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		350058 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		484281 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		VSIG8_HUMAN (14-258): 2.22e-54: 183: 26.60
+	Hs
		913999 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		348489 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		349841 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (118-299): 2.37e-19: 90.3: 16.33
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		348723 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		350246 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (24-138): 4.1e-09: 59.9: 14.66
+	Hs
		914506 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		507936 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		FGFR1_HUMAN (37-209): 5.59e-13: 71: 14.14
+	Hs
		508023 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		FGFR1_HUMAN (37-209): 5.59e-13: 71: 14.14
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (24-138): 4.1e-09: 59.9: 14.66