Protein: MED4
Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) (dp34)

Gene: MED4
Organism: Drosophila melanogaster
Interactions: 79
UniProt ID: Q9VS38

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045893 - positive regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

55673

MED9
Mediator of RNA polymerase II transcription subunit 9

3

1

High-throughput

0.843

High

1373450

MED21
Mediator of RNA polymerase II transcription subunit 21

2

1

High-throughput

0.767

High

1229240

MED6
Mediator of RNA polymerase II transcription subunit 6

2

1

Small-scale

0.737

High

1325926

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.618

High

1373446

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.618

High

858477

RFC2
Replication factor C subunit 2

2

0

High-throughput

0.598

High

1177208

Q7JUF2
Diego, isoform A

2

2

High-throughput

0.594

High

1325829

MED10
Mediator of RNA polymerase II transcription subunit 10

2

1

Small-scale

0.576

High

1361568

LARP
La-related protein 1

2

2

High-throughput

0.570

High

447597

ZEN1
Protein zerknuellt 1

1

0

High-throughput

0.486

High

1001480

Q0IGU7
HLH54F

1

0

High-throughput

0.486

High

1280205

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.486

High

1364617

Q9VEF5
Inhibitor of growth protein

1

0

High-throughput

0.486

High

1373441

Q9VW52
Precursor RNA processing 3, isoform A

1

0

High-throughput

0.486

High

56319

MED8
Mediator of RNA polymerase II transcription subunit 8

1

1

High-throughput

0.479

High

844386

DSH
Segment polarity protein dishevelled

1

1

High-throughput

0.479

High

954645

MED20
Mediator of RNA polymerase II transcription subunit 20

1

1

High-throughput

0.479

High

1180514

MED29
Mediator of RNA polymerase II transcription subunit 29

1

1

High-throughput

0.479

High

1182303

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.479

High

1279326

EBI
F-box-like/WD repeat-containing protein ebi

1

1

High-throughput

0.479

High

1359942

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

Small-scale

0.479

High

1364506

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.479

High

1365122

Q9VF03
Brahma associated protein 155 kDa

1

3

High-throughput

0.479

High

1371508

MED27
Mediator of RNA polymerase II transcription subunit 27

1

2

High-throughput

0.479

High

1372887

Q9VR42
Serine/threonine-protein kinase RIO3

1

1

High-throughput

0.479

High

1373435

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

High-throughput

0.479

High

1373436

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.479

High

1373440

MED11
Mediator of RNA polymerase II transcription subunit 11

1

1

High-throughput

0.479

High

1373443

BAP60
Brahma-associated protein of 60 kDa

1

2

High-throughput

0.479

High

1373445

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.479

High

1373447

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

1373448

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.479

High

1373452

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

High-throughput

0.479

High

1373454

MED15
Mediator of RNA polymerase II transcription subunit 15

1

2

High-throughput

0.479

High

871171

CNN
Centrosomin

1

1

High-throughput

0.464

High

1359119

A36DE
Accessory gland protein Acp36DE

1

2

High-throughput

0.464

High

1373449

Q9W3A1
Uncharacterized protein, isoform A

1

2

High-throughput

0.464

High

1373451

Q9XZ12
Protein FAM91A1

1

1

High-throughput

0.464

High

631327

BRM
ATP-dependent helicase brm

1

0

High-throughput

0.458

High

1176792

Q7JQT8
LD41464p

1

0

High-throughput

0.458

High

1364491

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

0

High-throughput

0.458

High

53668

A1Z904
Dystrobrevin

1

3

High-throughput

0.451

High

1213773

Q8INY5
RE08003p1

1

1

High-throughput

0.451

High

1368518

Q9VJ95
Protein tyrosine phosphatase 36E, isoform A

1

1

High-throughput

0.451

High

1372703

Q9VQS1
FI08260p

1

3

High-throughput

0.451

High

114479

M9PCH6
Omega, isoform H

1

1

High-throughput

0.439

High

115210

M9PEF7
Puratrophin-1-like, isoform D

1

1

High-throughput

0.439

High

1001137

Q0E9B2
Dystrobrevin

1

2

High-throughput

0.439

High

1228775

Q8MQJ7
Autophagy-related 1, isoform B

1

1

High-throughput

0.439

High

1373455

R9PY49
Uncharacterized protein, isoform C

1

3

High-throughput

0.439

High

1373456

X2JEH3
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

1250626

MESD
LDLR chaperone boca

1

1

High-throughput

0.437

High

1337346

LAR4
La-related protein Larp4B

1

2

High-throughput

0.437

High

1373438

Q9VUB7
PAX transcription activation domain interacting protein

1

1

High-throughput

0.437

High

1182364

Q7KU88
Puratrophin-1-like, isoform B

1

2

High-throughput

0.417

High

1373437

Q9VU14
Autophagy-related 1, isoform A

1

1

High-throughput

0.417

High

1373439

Q9VUH1
LD21715p

1

1

High-throughput

0.417

High

1367550

Q9VHV6
RE31520p

2

0

High-throughput

0.325

High

1372685

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.282

High

51665

A1Z6Q0
Klaroid, isoform D

1

0

High-throughput

0.265

Low

685617

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.265

Low

1249166

Q8SYC3
RE68569p

1

0

High-throughput

0.265

Low

1250313

GAP2
Ras GTPase-activating protein raskol

1

0

High-throughput

0.265

Low

1325851

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.265

Low

1359174

Q9V3U7
GEO12036p1

1

0

High-throughput

0.265

Low

1363635

S35B1
Solute carrier family 35 member B1 homolog

1

0

High-throughput

0.265

Low

1363899

NAA25
Phagocyte signaling-impaired protein

1

0

High-throughput

0.265

Low

1364018

Q9VDW9
LP03867p

1

0

High-throughput

0.265

Low

1367305

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.265

Low

1372839

Q9VR24
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1373442

Q9VX05
Uncharacterized protein

1

0

High-throughput

0.265

Low

1373444

Q9W0K9
LD10220p

1

0

High-throughput

0.265

Low

1373453

DNK
Deoxynucleoside kinase

1

0

High-throughput

0.265

Low

1369502

Q9VKI8
GH03305p

1

0

High-throughput

0.251

Low

1179966

Q7K485
Cathepsin D

1

0

High-throughput

0.249

Low

1279118

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

1280243

Q960F7
SD03629p

1

0

High-throughput

0.249

Low

1369828

Q9VL29
GEO11246p1

1

0

High-throughput

0.249

Low

1098404

NETA
Netrin-A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024