Protein: ZBT7A
Zinc finger and BTB domain-containing protein 7A (Factor binding IST protein 1) (FBI-1) (Factor that binds to inducer of short transcripts protein 1) (HIV-1 1st-binding protein 1) (Leukemia/lymphoma-related factor) (POZ and Krueppel erythroid myeloid ontogenic factor) (POK erythroid myeloid ontogenic factor) (Pokemon) (Pokemon 1) (TTF-I-interacting peptide 21) (TIP21) (Zinc finger protein 857A)

Gene: ZBT7A, ZBTB7A
Organism: Homo sapiens
Interactions: 137
UniProt ID: O95365

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 - transcription corepressor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

334483

ZBT7A
Zinc finger and BTB domain-containing protein 7A

3

19

Small-scale

0.857

High

334564

BCOR
BCL-6 corepressor

2

9

Small-scale

0.800

High

334498

ZBT48
Zinc finger and BTB domain-containing protein 48

1

19

Small-scale

0.724

High

334555

HDAC1
Histone deacetylase 1

6

20

Small-scale

0.723

High

334520

BCL6
B-cell lymphoma 6 protein

1

17

Small-scale

0.713

High

334561

IKBB
NF-kappa-B inhibitor beta

1

5

Small-scale

0.713

High

51757

ZBT7C
Zinc finger and BTB domain-containing protein 7C

1

19

High-throughput

0.691

High

334548

TF65
Transcription factor p65

3

8

Small-scale

0.661

High

334580

CRBN
Protein cereblon

1

6

Small-scale

0.647

High

316708

MTA2
Metastasis-associated protein MTA2

3

8

Small-scale

0.646

High

278195

NCOR1
Nuclear receptor corepressor 1

3

20

Small-scale

0.642

High

334600

NCOR2
Nuclear receptor corepressor 2

3

11

Small-scale

0.642

High

334488

P53
Cellular tumor antigen p53

2

11

Small-scale

0.624

High

334491

HS90A
Heat shock protein HSP 90-alpha

2

9

Small-scale

0.624

High

334499

ANDR
Androgen receptor

2

20

Small-scale

0.624

High

180133

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

16

Small-scale

0.618

High

212829

ZBT43
Zinc finger and BTB domain-containing protein 43

1

20

Small-scale

0.618

High

334492

SP1
Transcription factor Sp1

1

20

Small-scale

0.618

High

334508

IKBA
NF-kappa-B inhibitor alpha

1

5

Small-scale

0.618

High

334556

CUL3
Cullin-3

1

20

High-throughput

0.618

High

334562

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.618

High

334577

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

10

Small-scale

0.618

High

334591

ZBTB4
Zinc finger and BTB domain-containing protein 4

1

18

Small-scale

0.618

High

334553

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

15

Small-scale

0.596

High

334585

CHD8
Chromodomain-helicase-DNA-binding protein 8

2

16

Small-scale

0.596

High

334574

HDAC2
Histone deacetylase 2

2

20

Small-scale

0.594

High

334549

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

1

Small-scale

0.594

High

176381

ZBTB5
Zinc finger and BTB domain-containing protein 5

1

20

Small-scale

0.590

High

182011

ZBT22
Zinc finger and BTB domain-containing protein 22

1

20

Small-scale

0.590

High

334576

ZBT45
Zinc finger and BTB domain-containing protein 45

1

20

Small-scale

0.590

High

334551

TF3C1
General transcription factor 3C polypeptide 1

1

0

Small-scale

0.586

High

334489

RB
Retinoblastoma-associated protein

2

1

Small-scale

0.584

High

334563

RBBP7
Histone-binding protein RBBP7

2

5

Small-scale

0.584

High

334554

SMAD4
Mothers against decapentaplegic homolog 4

1

6

Small-scale

0.573

High

334569

HOMEZ
Homeobox and leucine zipper protein Homez

1

2

High-throughput

0.573

High

334487

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

334484

MBD3
Methyl-CpG-binding domain protein 3

1

5

Small-scale

0.561

High

334501

XRCC6
X-ray repair cross-complementing protein 6

1

5

Small-scale

0.561

High

334502

XRCC5
X-ray repair cross-complementing protein 5

1

5

Small-scale

0.561

High

334543

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

Small-scale

0.561

High

334571

P66B
Transcriptional repressor p66-beta

1

7

Small-scale

0.549

High

334594

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

17

High-throughput

0.541

High

334523

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.536

High

334526

SOX2
Transcription factor SOX-2

1

19

High-throughput

0.536

High

334587

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

17

Small-scale

0.506

High

334539

UBC9
SUMO-conjugating enzyme UBC9

1

4

Small-scale

0.501

High

123023

DX39A
ATP-dependent RNA helicase DDX39A

1

7

Small-scale

0.479

High

135434

DNM1L
Dynamin-1-like protein

1

5

Small-scale

0.479

High

142769

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

154595

ARI1A
AT-rich interactive domain-containing protein 1A

1

7

Small-scale

0.479

High

188137

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.479

High

243493

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

16

Small-scale

0.479

High

285756

SF3B1
Splicing factor 3B subunit 1

1

5

Small-scale

0.479

High

325633

UBR5
E3 ubiquitin-protein ligase UBR5

1

12

Small-scale

0.479

High

333904

SMC2
Structural maintenance of chromosomes protein 2

1

5

Small-scale

0.479

High

334485

ACL6A
Actin-like protein 6A

1

7

Small-scale

0.479

High

334486

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

Small-scale

0.479

High

334490

H2B1J
Histone H2B type 1-J

1

4

Small-scale

0.479

High

334493

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

Small-scale

0.479

High

334494

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

334495

VIME
Vimentin

1

11

Small-scale

0.479

High

334497

PARP1
Poly [ADP-ribose] polymerase 1

1

13

Small-scale

0.479

High

334500

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

334503

ETS1
Protein C-ets-1

1

7

Small-scale

0.479

High

334504

RL35A
Large ribosomal subunit protein eL33

1

1

Small-scale

0.479

High

334505

RL7
Large ribosomal subunit protein uL30

1

7

Small-scale

0.479

High

334506

TAF1
Transcription initiation factor TFIID subunit 1

1

20

High-throughput

0.479

High

334507

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

6

Small-scale

0.479

High

334509

DNMT1
DNA

1

9

Small-scale

0.479

High

334510

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

Small-scale

0.479

High

334511

SHC1
SHC-transforming protein 1

1

9

Small-scale

0.479

High

334512

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

18

Small-scale

0.479

High

334513

RFC4
Replication factor C subunit 4

1

3

Small-scale

0.479

High

334514

RFC1
Replication factor C subunit 1

1

7

Small-scale

0.479

High

334515

SRBP1
Sterol regulatory element-binding protein 1

1

10

Small-scale

0.479

High

334516

IF4A3
Eukaryotic initiation factor 4A-III

1

7

Small-scale

0.479

High

334517

RS19
Small ribosomal subunit protein eS19

1

6

Small-scale

0.479

High

334518

TCPZ
T-complex protein 1 subunit zeta

1

6

Small-scale

0.479

High

334521

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

Small-scale

0.479

High

334522

CBX5
Chromobox protein homolog 5

1

20

Small-scale

0.479

High

334524

RL28
Large ribosomal subunit protein eL28

1

6

Small-scale

0.479

High

334525

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

Small-scale

0.479

High

334527

SOX9
Transcription factor SOX-9

1

16

Small-scale

0.479

High

334529

DYN2
Dynamin-2

1

5

Small-scale

0.479

High

334531

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

16

Small-scale

0.479

High

334532

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

9

Small-scale

0.479

High

334534

IF4A1
Eukaryotic initiation factor 4A-I

1

7

Small-scale

0.479

High

334536

RS8
Small ribosomal subunit protein eS8

1

2

Small-scale

0.479

High

334537

RS14
Small ribosomal subunit protein uS11

1

5

Small-scale

0.479

High

334538

H4
Histone H4

1

8

High-throughput

0.479

High

334540

EF1A1
Elongation factor 1-alpha 1

1

3

Small-scale

0.479

High

334542

GTF2I
General transcription factor II-I

1

2

Small-scale

0.479

High

334544

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

11

Small-scale

0.479

High

334545

E2F1
Transcription factor E2F1

1

1

Small-scale

0.479

High

334546

TFAP4
Transcription factor AP-4

1

1

Small-scale

0.479

High

334547

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

1

Small-scale

0.479

High

334550

DHX9
ATP-dependent RNA helicase A

1

9

Small-scale

0.479

High

334552

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

334558

SMC1A
Structural maintenance of chromosomes protein 1A

1

5

Small-scale

0.479

High

334559

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

15

Small-scale

0.479

High

334560

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

334566

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

Small-scale

0.479

High

334567

P66A
Transcriptional repressor p66-alpha

1

7

Small-scale

0.479

High

334568

MGAP
MAX gene-associated protein

1

3

Small-scale

0.479

High

334570

SMRC2
SWI/SNF complex subunit SMARCC2

1

13

Small-scale

0.479

High

334572

GCN1
Stalled ribosome sensor GCN1

1

7

Small-scale

0.479

High

334573

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

334575

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

9

Small-scale

0.479

High

334578

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

334579

SIN3A
Paired amphipathic helix protein Sin3a

1

3

Small-scale

0.479

High

334581

FEV
Protein FEV

1

6

High-throughput

0.479

High

334582

MBB1A
Myb-binding protein 1A

1

3

Small-scale

0.479

High

334584

DDX31
ATP-dependent DNA helicase DDX31

1

5

Small-scale

0.479

High

334586

DDX21
Nucleolar RNA helicase 2

1

8

Small-scale

0.479

High

334588

SMC4
Structural maintenance of chromosomes protein 4

1

6

Small-scale

0.479

High

334589

MDN1
Midasin

1

8

Small-scale

0.479

High

334592

DNM3B
DNA

1

5

Small-scale

0.479

High

334593

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

334595

MAGD2
Melanoma-associated antigen D2

1

9

Small-scale

0.479

High

334597

SMC3
Structural maintenance of chromosomes protein 3

1

5

Small-scale

0.479

High

334598

RUVB2
RuvB-like 2

1

2

Small-scale

0.479

High

334599

RUVB1
RuvB-like 1

1

2

Small-scale

0.479

High

334496

RS17
Small ribosomal subunit protein eS17

1

0

Small-scale

0.458

High

334528

FAS
Fatty acid synthase

1

0

Small-scale

0.458

High

334535

RL27
Large ribosomal subunit protein eL27

1

0

Small-scale

0.458

High

334565

SRCAP
Helicase SRCAP

1

11

Small-scale

0.457

High

334590

GRHL1
Grainyhead-like protein 1 homolog

1

7

High-throughput

0.445

High

105018

APRIO
Alternative prion protein

1

6

High-throughput

0.437

High

334519

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

Small-scale

0.437

High

334530

TCPD
T-complex protein 1 subunit delta

1

5

Small-scale

0.437

High

334533

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

Small-scale

0.437

High

334541

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

1

Small-scale

0.437

High

334557

RBM39
RNA-binding protein 39

1

7

Small-scale

0.437

High

334583

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low

334596

DIM1
Dimethyladenosine transferase

1

0

Small-scale

0.249

Low

171380

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025