HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 30194290, 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~fn3
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0044877 - protein-containing complex binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 189
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024