HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1181
+	Hs
		349109 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		566881 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		566866 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		566871 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		ITA2_HUMAN (1-1181): 0: 1250: 100.00
+	Hs
		349134 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32
+	Hs
		349128 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		348513 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		613251 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		349097 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73
+	Hs
		349879 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		613233 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		613237 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10
+	Hs
		349073 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		348477 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		530549 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73
+	Hs
		443078 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		349814 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		443061 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		ITA5_HUMAN (27-512): 7.68e-47: 185: 15.07
+	Hs
		530555 RAP1B_HUMAN (1-165): 1.02e-62: 193: 57.49		ITA4_HUMAN (2-513): 1.18e-52: 203: 20.73
+	Mm
		919010 RAB1A_MOUSE (4-187): 7.4e-74: 222: 34.36		ITA2B_MOUSE (4-282): 3.44e-23: 109: 14.67