Protein: NVL
Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein)

Gene: NVL
Organism: Homo sapiens
Interactions: 162
UniProt ID: O15381

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005697 - telomerase holoenzyme complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

188409

BRD4
Bromodomain-containing protein 4

2

12

High-throughput

0.754

High

188422

NPM
Nucleophosmin

5

2

High-throughput

0.718

High

188467

RS6
Small ribosomal subunit protein eS6

3

3

High-throughput

0.656

High

188492

IF16
Gamma-interferon-inducible protein 16

3

4

High-throughput

0.656

High

188514

PRR11
Proline-rich protein 11

3

0

High-throughput

0.638

High

139437

PESC
Pescadillo homolog

2

3

High-throughput

0.628

High

188448

RBM34
RNA-binding protein 34

2

4

High-throughput

0.628

High

188456

MECP2
Methyl-CpG-binding protein 2

2

1

High-throughput

0.628

High

188518

ZN512
Zinc finger protein 512

2

4

High-throughput

0.628

High

188525

RBM4
RNA-binding protein 4

2

6

High-throughput

0.628

High

188420

HSPB1
Heat shock protein beta-1

2

2

High-throughput

0.628

High

188474

RED1
Double-stranded RNA-specific editase 1

2

4

High-throughput

0.614

High

188473

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

High-throughput

0.606

High

188404

RRP8
Ribosomal RNA-processing protein 8

2

0

High-throughput

0.602

High

188493

PKHO1
Pleckstrin homology domain-containing family O member 1

2

0

High-throughput

0.602

High

188511

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

188526

MAK16
Protein MAK16 homolog

2

0

High-throughput

0.602

High

188532

SSF1
Suppressor of SWI4 1 homolog

2

0

High-throughput

0.602

High

188534

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

2

0

High-throughput

0.602

High

188444

RL13A
Large ribosomal subunit protein uL13

2

5

High-throughput

0.601

High

188465

RL7A
Large ribosomal subunit protein eL8

2

4

High-throughput

0.601

High

188471

RL11
Large ribosomal subunit protein uL5

2

2

High-throughput

0.601

High

96579

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

188418

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

188424

PARP1
Poly [ADP-ribose] polymerase 1

2

2

High-throughput

0.584

High

188460

FGF8
Fibroblast growth factor 8

2

1

High-throughput

0.574

High

188545

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.553

High

182217

WDR46
WD repeat-containing protein 46

1

6

High-throughput

0.536

High

188403

MAGB2
Melanoma-associated antigen B2

1

3

High-throughput

0.536

High

188411

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

6

High-throughput

0.536

High

188412

NPM3
Nucleoplasmin-3

1

4

High-throughput

0.536

High

188417

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

6

High-throughput

0.536

High

188421

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.536

High

188428

RL17
Large ribosomal subunit protein uL22

1

5

High-throughput

0.536

High

188431

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

4

High-throughput

0.536

High

188432

H1T
Histone H1t

1

1

High-throughput

0.536

High

188434

RL10
Large ribosomal subunit protein uL16

1

4

High-throughput

0.536

High

188440

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.536

High

188446

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.536

High

188450

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

188452

NOP2
28S rRNA

1

2

High-throughput

0.536

High

188453

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

188462

RL15
Large ribosomal subunit protein eL15

1

3

High-throughput

0.536

High

188463

RHOA
Transforming protein RhoA

1

11

High-throughput

0.536

High

188464

RS14
Small ribosomal subunit protein uS11

1

4

High-throughput

0.536

High

188466

RL23A
Large ribosomal subunit protein uL23

1

2

High-throughput

0.536

High

188477

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

7

High-throughput

0.536

High

188481

RL18
Large ribosomal subunit protein eL18

1

2

High-throughput

0.536

High

188483

ILF3
Interleukin enhancer-binding factor 3

1

6

High-throughput

0.536

High

188486

SRSF6
Serine/arginine-rich splicing factor 6

1

7

High-throughput

0.536

High

188487

CUL3
Cullin-3

1

12

High-throughput

0.536

High

188488

EXOS2
Exosome complex component RRP4

1

2

High-throughput

0.536

High

188500

KI21A
Kinesin-like protein KIF21A

1

7

High-throughput

0.536

High

188503

CUL9
Cullin-9

1

8

High-throughput

0.536

High

188508

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

2

High-throughput

0.536

High

188517

MAGBA
Melanoma-associated antigen B10

1

3

High-throughput

0.536

High

188535

DDX21
Nucleolar RNA helicase 2

1

6

High-throughput

0.536

High

188540

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.536

High

188542

ZBT47
Zinc finger and BTB domain-containing protein 47

1

2

High-throughput

0.536

High

188544

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

188549

SRPK3
SRSF protein kinase 3

1

6

High-throughput

0.536

High

188554

RL36
Large ribosomal subunit protein eL36

1

3

High-throughput

0.536

High

188405

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.515

High

188407

KIF1B
Kinesin-like protein KIF1B

1

11

High-throughput

0.515

High

188425

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

6

High-throughput

0.515

High

188436

NOS3
Nitric oxide synthase 3

1

3

High-throughput

0.515

High

188437

MERL
Merlin

1

7

High-throughput

0.515

High

188442

SYUA
Alpha-synuclein

1

3

High-throughput

0.515

High

188447

PERI
Peripherin

1

9

High-throughput

0.515

High

188459

ATX1
Ataxin-1

1

3

High-throughput

0.515

High

188461

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

4

High-throughput

0.515

High

188476

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.515

High

188485

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.515

High

188490

DCTN1
Dynactin subunit 1

1

6

High-throughput

0.515

High

188551

RNF11
RING finger protein 11

1

6

High-throughput

0.515

High

188555

TF3C3
General transcription factor 3C polypeptide 3

1

3

High-throughput

0.515

High

188429

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

188441

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

188454

CDX1
Homeobox protein CDX-1

1

0

High-throughput

0.513

High

188496

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

188501

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

188509

PHF10
PHD finger protein 10

1

0

High-throughput

0.513

High

188520

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.513

High

188522

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.513

High

188537

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

188546

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

188472

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.508

High

188531

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.508

High

188548

TTF2
Transcription termination factor 2

1

5

Small-scale

0.508

High

188489

DPYL1
Dihydropyrimidinase-related protein 1

1

10

High-throughput

0.494

High

47286

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

188478

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

188410

MPPB
Mitochondrial-processing peptidase subunit beta

1

3

High-throughput

0.489

High

188433

KALM
Anosmin-1

1

2

High-throughput

0.489

High

188502

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

188552

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

128629

MEN1
Menin

1

2

High-throughput

0.479

High

156706

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

188402

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

188406

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

188408

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

188415

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

188416

KI20A
Kinesin-like protein KIF20A

1

15

High-throughput

0.479

High

188419

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

11

High-throughput

0.479

High

188423

HS90A
Heat shock protein HSP 90-alpha

1

8

High-throughput

0.479

High

188426

ANDR
Androgen receptor

1

10

High-throughput

0.479

High

188427

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.479

High

188435

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

188438

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

188439

RL22
Large ribosomal subunit protein eL22

1

3

High-throughput

0.479

High

188443

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

188445

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

188451

RECQ1
ATP-dependent DNA helicase Q1

1

8

High-throughput

0.479

High

188455

RL14
Large ribosomal subunit protein eL14

1

3

High-throughput

0.479

High

188458

PLK1
Serine/threonine-protein kinase PLK1

1

10

High-throughput

0.479

High

188468

H2B1C
Histone H2B type 1-C/E/F/G/I

1

6

High-throughput

0.479

High

188469

RS24
Small ribosomal subunit protein eS24

1

3

High-throughput

0.479

High

188470

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

188475

H33
Histone H3.3

1

6

High-throughput

0.479

High

188479

EXOSX
Exosome complex component 10

1

3

High-throughput

0.479

High

188480

KIF23
Kinesin-like protein KIF23

1

9

High-throughput

0.479

High

188482

ILF2
Interleukin enhancer-binding factor 2

1

3

High-throughput

0.479

High

188484

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.479

High

188491

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

188495

IFIX
Pyrin and HIN domain-containing protein 1

1

4

High-throughput

0.479

High

188504

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

188505

SLX4
Structure-specific endonuclease subunit SLX4

1

7

High-throughput

0.479

High

188506

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

188510

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

188512

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

188515

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

188516

CEP19
Centrosomal protein of 19 kDa

1

1

High-throughput

0.479

High

188521

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

188523

VRK1
Serine/threonine-protein kinase VRK1

1

4

High-throughput

0.479

High

188524

DDX23
Probable ATP-dependent RNA helicase DDX23

1

6

High-throughput

0.479

High

188527

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

9

High-throughput

0.479

High

188528

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

188530

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

188533

ANLN
Anillin

1

3

High-throughput

0.479

High

188536

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

188538

DCA13
DDB1- and CUL4-associated factor 13

1

9

Small-scale

0.479

High

188539

DJC17
DnaJ homolog subfamily C member 17

1

8

High-throughput

0.479

High

188541

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

188543

XPO7
Exportin-7

1

7

High-throughput

0.479

High

188547

RL26L
Ribosomal protein uL24-like

1

3

High-throughput

0.479

High

188550

CE164
Centrosomal protein of 164 kDa

1

9

High-throughput

0.479

High

188449

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

188499

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

188553

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

188494

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

188498

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

188513

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.437

High

188529

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

188497

Q6T424
Tumor differentiation factor

1

0

Small-scale

0.426

High

69913

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.407

High

188507

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

9

High-throughput

0.407

High

188430

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

2

0

High-throughput

0.324

High

188413

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.279

Low

188457

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

188519

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

188414

WFS1
Wolframin

1

0

High-throughput

0.268

Low

188401

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025