HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 359
+	Hs
		349192 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GNAQ_HUMAN (1-359): 1.3e-168: 475: 90.25
+	Hs
		670449 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00
+	Hs
		349793 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14
+	Hs
		349815 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57
+	Hs
		391368 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14
+	Hs
		348605 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83
+	Hs
		450998 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNAO_HUMAN (7-358): 1.96e-161: 457: 50.28
+	Hs
		391371 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14
+	Hs
		325962 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNA14_HUMAN (9-359): 2.8e-158: 449: 82.34
+	Hs
		350051 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83
+	Hs
		349832 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAT1_HUMAN (7-358): 4.31e-148: 423: 49.44
+	Hs
		350169 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNA13_HUMAN (8-358): 1.24e-143: 413: 45.00
+	Hs
		350096 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNA12_HUMAN (24-358): 8.97e-95: 288: 43.66