HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 205
+	Hs
		349231 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		348601 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		918874 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Mm
		918986 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00
+	Hs
		349344 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Mm
		895595 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB8B_MOUSE (4-203): 5.26e-86: 254: 52.50
+	Mm
		1161509 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1B_MOUSE (4-205): 1e-85: 253: 91.09
+	Mm
		1161510 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB13_MOUSE (4-202): 5.42e-86: 253: 50.25
+	Hs
		895026 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		348682 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Zm
		73944 B4FAE1_MAIZE (4-187): 8.1e-78: 232: 32.82		B4FAE1_MAIZE (4-204): 3.9e-87: 257: 78.71
+	Hs
		895217 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		895264 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		350033 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		895216 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1C_HUMAN (4-205): 2.97e-83: 247: 87.62
+	Hs
		350197 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		350016 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		895020 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Mm
		877193 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB8A_MOUSE (4-199): 4.88e-74: 224: 54.08
+	Mm
		877189 RAB8B_MOUSE (4-189): 1.99e-75: 226: 32.00		RAB8A_MOUSE (4-199): 4.88e-74: 224: 54.08