HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: EM55 (Q00013)
55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1)
Gene: MPP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30442766, 30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 466
+	Hs
		349246 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EM55_HUMAN (1-466): 2.38e-154: 448: 100.00
+	Hs
		348614 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EM55_HUMAN (1-466): 2.38e-154: 448: 100.00
+	Hs
		159212 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CSKP_HUMAN (6-466): 3.61e-126: 390: 49.11
+	Hs
		350623 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PALS2_HUMAN (29-466): 2.44e-134: 400: 39.00
+	Hs
		349476 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PALS1_HUMAN (5-465): 9.92e-121: 369: 28.20
+	Hs
		159130 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CSKP_HUMAN (6-466): 3.61e-126: 390: 49.11
+	Hs
		349383 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MPP7_HUMAN (15-466): 1.99e-118: 360: 31.25
+	Hs
		1070296 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PALS1_HUMAN (5-465): 9.92e-121: 369: 28.20
+	Hs
		348711 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MPP7_HUMAN (15-466): 1.99e-118: 360: 31.25
+	Hs
		1070233 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MPP7_HUMAN (15-466): 1.99e-118: 360: 31.25
+	Hs
		350339 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PALS1_HUMAN (5-465): 9.92e-121: 369: 28.20
+	Hs
		350231 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MPP7_HUMAN (15-466): 1.99e-118: 360: 31.25
+	Hs
		895117 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		MPP7_HUMAN (15-466): 1.99e-118: 360: 31.25
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (62-217): 1.93e-17: 87.2: 17.86
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (62-217): 1.93e-17: 87.2: 17.86
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (71-141): 3.36e-14: 77.2: 20.51
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (62-217): 1.93e-17: 87.2: 17.86
+	Hs
		350124 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG1_HUMAN (62-217): 1.93e-17: 87.2: 17.86
+	Hs
		895057 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		DLG1_HUMAN (62-217): 1.93e-17: 87.2: 17.86
+	Hs
		350420 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		DLG3_HUMAN (71-141): 3.36e-14: 77.2: 20.51