HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: CDK17 (Q00537)
Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)
Gene: CDK17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 523
+	Hs
		349133 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		348618 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		960367 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		350078 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		895041 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Rn
		442950 RASK_RAT (1-189): 4.5e-77: 230: 98.94		Q6P751_RAT (189-484): 6.48e-160: 457: 52.01
+	Hs
		914011 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		348617 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CDK5_HUMAN (189-479): 3.6e-139: 405: 55.63
+	Hs
		300616 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		349801 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CDK1_HUMAN (189-478): 5.1e-143: 415: 54.95
+	Hs
		300617 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Dm
		618430 RALA_DROME (4-182): 3.4e-60: 187: 52.22		CDK2_DROME (189-484): 2.14e-129: 380: 49.01