HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0019003 - GDP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 218
+	Hs
		349344 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		348682 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		349231 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		348601 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		918874 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Mm
		918986 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1A_MOUSE (1-215): 2.92e-90: 265: 43.26
+	Mm
		1161509 RAB35_MOUSE (4-187): 1.09e-82: 244: 31.28		RAB1B_MOUSE (4-215): 3.54e-86: 255: 44.81
+	Hs
		350033 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Zm
		73944 B4FAE1_MAIZE (4-187): 8.1e-78: 232: 32.82		B4FAE1_MAIZE (4-216): 1.33e-89: 263: 44.13
+	Hs
		350037 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		895026 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		913992 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		918846 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		895264 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Mm
		1321974 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		RAB1B_MOUSE (4-215): 3.54e-86: 255: 44.81
+	Mm
		919000 RAB1A_MOUSE (4-187): 7.4e-74: 222: 34.36		RAB1B_MOUSE (4-215): 3.54e-86: 255: 44.81
+	Hs
		884467 RAB1A_HUMAN (4-187): 7.4e-74: 222: 34.36		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		895084 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895204 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RAB2B_HUMAN (8-178): 1.08e-61: 193: 56.14