HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SDK2 (Q58EX2)
Protein sidekick-2
Gene: SDK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 2172
+	Hs
		914108 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		SDK2_HUMAN (1-2172): 0: 1411: 100.00
+	Hs
		350296 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SDK1_HUMAN (185-2128): 0: 610: 17.65
+	Hs
		349083 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTPRF_HUMAN (3-1100): 2.16e-103: 372: 17.35
+	Hs
		489965 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTPRF_HUMAN (3-1100): 2.16e-103: 372: 17.35
+	Hs
		348841 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		NEO1_HUMAN (511-1507): 7.11e-102: 363: 18.19
+	Hs
		349822 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTPRF_HUMAN (3-1100): 2.16e-103: 372: 17.35
+	Hs
		489934 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		PTPRF_HUMAN (3-1100): 2.16e-103: 372: 17.35
+	Hs
		350424 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		NEO1_HUMAN (511-1507): 7.11e-102: 363: 18.19
+	Hs
		1031987 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PTPRS_HUMAN (20-1072): 4.58e-89: 326: 16.71
+	Mm
		514129 RB11A_MOUSE (4-184): 2.43e-72: 219: 33.88		L1CAM_MOUSE (1297-2167): 1.24e-34: 147: 11.07
+	Hs
		350405 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		TITIN_HUMAN (503-874): 8.8e-10: 66.7: 12.67
+	Hs
		914253 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TITIN_HUMAN (503-874): 8.8e-10: 66.7: 12.67