HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: RHG21 (Q5T5U3)
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)
Gene: ARHGAP21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30639242, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGAP
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1958
+	Hs
		349384 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG21_HUMAN (1-1958): 0: 1739: 100.00
+	Hs
		1070234 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG21_HUMAN (1-1958): 0: 1739: 100.00
+	Hs
		895119 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		RHG21_HUMAN (1-1958): 0: 1739: 100.00
+	Hs
		349535 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ARAP2_HUMAN (461-1674): 2.78e-114: 404: 13.08
+	Hs
		350406 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ARAP2_HUMAN (461-1674): 2.78e-114: 404: 13.08
+	Hs
		895065 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		MYO9B_HUMAN (528-1527): 2.57e-108: 388: 12.88
+	Hs
		350325 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG12_HUMAN (541-1339): 2.94e-113: 384: 21.71
+	Hs
		49624 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG10_HUMAN (883-1558): 8.64e-95: 328: 17.84
+	Hs
		349370 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		RHG29_HUMAN (906-1715): 6.23e-86: 311: 16.82
+	Hs
		64708 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RHG32_HUMAN (975-1909): 3.2e-84: 310: 16.63
+	Hs
		64637 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG32_HUMAN (975-1909): 3.2e-84: 310: 16.63
+	Hs
		350527 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RHG39_HUMAN (510-1341): 1.78e-85: 307: 15.07
+	Hs
		253300 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SRGP2_HUMAN (652-1769): 9.4e-84: 302: 13.96
+	Hs
		349280 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ABR_HUMAN (1130-1341): 1.91e-65: 242: 34.55
+	Hs
		506558 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		BCR_HUMAN (1142-1311): 4.29e-23: 110: 40.00